Research at the Center for Regenerative Therapies Dresden (CRTD) at TU Dresden focuses on discovering principles of cell and tissue regeneration, and leveraging this for recognition, treatment, and reversal of diseases. The CRTD is well positioned for this challenge with its diversity in model organisms, organs, and disease systems and its range of methodological approaches from basic research to validation projects and clinical studies. The CRTD links the bench to the clinic, and scientists to clinicians to bring expertise in stem cells, gene-editing, and regeneration towards innovative therapies for metabolic, osteo-hematological, and neurological diseases.