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Radiation-induced morphea of the breast - characterization and treatment of fibroblast dysfunction with repurposed mesalazine

Künzel, S. R., Klapproth, E., Zimmermann, N., Kämmerer, S., Schubert, M., Künzel, K. & Hoffmann, M. & 11 others, Drukewitz, S., Vehlow, A., Eitler, J., Arriens, M., Thiel, J., Kronstein-Wiedemann, R., Tietze, M., Beissert, S., Renner, B., El-Armouche, A. & Günther, C., 30 Oct 2024, In: Scientific reports. 14 (2024), 1, 16 p., 26132.

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Investigation of mesalazine as an antifibrotic drug following myocardial infarction in male mice

Künzel, S. R., Winter, L., Hoffmann, M., Kant, T. A., Thiel, J., Kronstein‐Wiedemann, R. & Klapproth, E. & 3 others, Lorenz, K., El‐Armouche, A. & Kämmerer, S., Sept 2023, In: Physiological reports. 11, 17, e15809.

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Diminished PLK2 Induces Cardiac Fibrosis and Promotes Atrial Fibrillation

Künzel, S. R. (Joint first author), Hoffmann, M. (Joint first author), Weber, S., Künzel, K., Kämmerer, S., Günscht, M. & Klapproth, E. & 25 others, Rausch, J. S. E., Sadek, M. S., Kolanowski, T., Meyer-Roxlau, S., Piorkowski, C., Tugtekin, S. M., Rose-John, S., Yin, X., Mayr, M., Kuhlmann, J. D., Wimberger, P., Grützmann, K., Herzog, N., Küpper, J.-H., O’Reilly, M., Kabir, S. N., Sommerfeld, L. C., Guan, K., Wielockx, B., Fabritz, L., Nattel, S., Ravens, U., Dobrev, D., Wagner, M. (Joint last author) & El-Armouche, A. (Joint last author), Oct 2021, In: Circulation research. 129, 8, p. 804-820 17 p.

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Systemic mesalazine treatment prevents spontaneous skin fibrosis in PLK2-deficient mice

Newe, M. (Joint first author), Kant, T. A. (Joint first author), Hoffmann, M. (Joint first author), Rausch, J. S. E., Winter, L., Künzel, K. & Klapproth, E. & 2 others, Günther, C. & Künzel, S. R. (Last author), Aug 2021, In: Naunyn-Schmiedeberg's archives of pharmacology. 394, 11, p. 2233-2244 12 p.

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