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Dr. Mario Schubert
Person

Affiliations

Institute of Pharmacology and Toxicology
- Academic Staff
- mario.schubert1@tu-dresden.de

Research interests

Highly interested in molecular pharmacology and understaning molecular pathomechanisms of heart disease. In our research, we use iPSC-derived caridomyocytes as a human model system to study phsiology and pathophysiology by applying a variety of different methods including microphysiological cell culture chip systems, 3D tissue engineering and CRISPR-Cas9 genome editing.

Identification Numbers

ORCID	0000-0002-8375-8233
Scopus author ID	57210942570

Radiation-induced morphea of the breast - characterization and treatment of fibroblast dysfunction with repurposed mesalazine

Künzel, S. R., Klapproth, E., Zimmermann, N., Kämmerer, S., Schubert, M., Künzel, K., Hoffmann, M., & 11 othersDrukewitz, S., Vehlow, A., Eitler, J., Arriens, M., Thiel, J., Kronstein-Wiedemann, R., Tietze, M., Beissert, S., Renner, B., El-Armouche, A. & Günther, C., 30 Oct 2024, In: Scientific reports. 14, 1, 26132.

Research output: Contribution to journal › Research article › Contributed › peer-review

Symmetric Dimethylarginine Predicts Previously Undetected Atrial Fibrillation in Patients With Ischemic Stroke

Hannemann, J., Wasser, K., Mileva, Y., Kleinsang, F., Schubert, M., Schwedhelm, E., Guan, K., & 2 othersWachter, R. & Böger, R., 3 Sept 2024, In: Journal of the American Heart Association. 13, 17, p. e034994 e034994.

Research output: Contribution to journal › Research article › Contributed › peer-review

Gene therapy with phosphodiesterases 2A and 4B ameliorates heart failure and arrhythmias by improving subcellular cAMP compartmentation

Pavlaki, N., Froese, A., Li, W., De Jong, K. A., Geertz, B., Subramanian, H., Mohagaonkar, S., & 10 othersLuo, X., Schubert, M., Wiegmann, R., Margaria, J. P., Ghigo, A., Kämmerer, S., Hirsch, E., El-Armouche, A., Guan, K. & Nikolaev, V. O., 1 Jun 2024, In: Cardiovascular research. 120, 9, p. 1011-1023 13 p.

Research output: Contribution to journal › Research article › Contributed › peer-review

Novel high-dense microelectrode array based multimodal bioelectronic monitoring system for cardiac arrhythmia re-entry analysis

Schmidt, S., Li, W., Schubert, M., Binnewerg, B., Prönnecke, C., Zitzmann, F. D., Bulst, M., & 4 othersWegner, S., Meier, M., Guan, K. & Jahnke, H. G., 15 May 2024, In: Biosensors and Bioelectronics. 252, 116120.

Research output: Contribution to journal › Research article › Contributed › peer-review

C-terminal variants in CDC42 drive type I interferon-dependent autoinflammation in NOCARH syndrome reversible by ruxolitinib

Kapp, F. G., Kretschmer, S., Beckmann, C. C. A., Wäsch, L., Molitor, A., Carapito, R., Schubert, M., & 25 othersLucas, N., Conrad, S., Poignant, S., Isidor, B., Rohlfs, M., Kisaarslan, A. P., Schanze, D., Zenker, M., Schmitt-Graeff, A., Strahm, B., Peters, A., Yoshimi, A., Driever, W., Zillinger, T., Günther, C., Maharana, S., Guan, K., Klein, C., Ehl, S., Niemeyer, C. M., Unal, E., Bahram, S., Hauck, F., Lee-Kirsch, M. A. & Speckmann, C., Nov 2023, In: Clinical immunology. 256, 109777.

Research output: Contribution to journal › Case report › Contributed › peer-review

View all research output (23)

Advanced Maturation of iPSC-derived cardiomyocytes in 2D culture

Schubert, M. (Speaker)

25 Nov 2022

Activity: Talk or presentation at external institutions/events › Talk/Presentation › Invited

Oslo University Hospital

Schubert, M. (Visitor), Guan-Schmidt, K. (Visitor)

21 Sept 2022 → 23 Sept 2022

Activity: Visiting external institutions › Cooperations or projects

View all activities (2)

Etablierung eines humanen Multi-Organ-on-a-Chip Modells zur Untersuchung der Monozyten- und Makrophagenfunktion nach Ischämie-Reperfusionsschädigung

Schubert, M. (Recipient), 20 Oct 2023

Prize: Fellow/scholarship › Other fellow/scholarship

View all prizes (4)

Metabolische Reifung und Charakterisierung von humanen künstlichen Herzmuskeln

Schubert, M.

5 Oct 2023

1 Media contribution

Press/Media

View all press/media (1)

Research Portal of the TU Dresden

Dr. Mario Schubert
Person

Affiliations

Research interests

Identification Numbers

Related content

Radiation-induced morphea of the breast - characterization and treatment of fibroblast dysfunction with repurposed mesalazine

Symmetric Dimethylarginine Predicts Previously Undetected Atrial Fibrillation in Patients With Ischemic Stroke

Gene therapy with phosphodiesterases 2A and 4B ameliorates heart failure and arrhythmias by improving subcellular cAMP compartmentation

Novel high-dense microelectrode array based multimodal bioelectronic monitoring system for cardiac arrhythmia re-entry analysis

C-terminal variants in CDC42 drive type I interferon-dependent autoinflammation in NOCARH syndrome reversible by ruxolitinib

Advanced Maturation of iPSC-derived cardiomyocytes in 2D culture

Oslo University Hospital

Etablierung eines humanen Multi-Organ-on-a-Chip Modells zur Untersuchung der Monozyten- und Makrophagenfunktion nach Ischämie-Reperfusionsschädigung

MeDDrive Grant 2022

MeDDrive Start Grant

Max-Kade Fellowship

Metabolische Reifung und Charakterisierung von humanen künstlichen Herzmuskeln