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Dr. Mario Schubert

Person

Research interests

Highly interested in molecular pharmacology and understaning molecular pathomechanisms of heart disease. In our research, we use iPSC-derived caridomyocytes as a human model system to study phsiology and pathophysiology by applying a variety of different methods including microphysiological cell culture chip systems, 3D tissue engineering and CRISPR-Cas9 genome editing. 

Identification Numbers

ORCID Orcid 0000-0002-8375-8233, external link
Scopus author ID 57210942570

Related content

Radiation-induced morphea of the breast - characterization and treatment of fibroblast dysfunction with repurposed mesalazine

Künzel, S. R., Klapproth, E., Zimmermann, N., Kämmerer, S., Schubert, M., Künzel, K. & Hoffmann, M. & 11 others, Drukewitz, S., Vehlow, A., Eitler, J., Arriens, M., Thiel, J., Kronstein-Wiedemann, R., Tietze, M., Beissert, S., Renner, B., El-Armouche, A. & Günther, C., 30 Oct 2024, In: Scientific reports. 14 (2024), 1, 16 p., 26132.

Research output: Contribution to journal › Research article › Contributed › peer-review

Long-term electrostimulation strongly enhances the expression of TFAM target genes and mitochondrial development of induced pluripotent stem cell-derived cardiomyocytes

Schubert, M., Li, W., Luo, X., Strano, A., Fischer, K., Pöche, J. & Ulbricht, Y. & 4 others, Lesche, M., El-Armouche, A., Dahl, A. & Guan, K., 12 Sept 2024.

Research output: Contribution to conferences › Poster › Contributed

Symmetric Dimethylarginine Predicts Previously Undetected Atrial Fibrillation in Patients With Ischemic Stroke

Hannemann, J., Wasser, K., Mileva, Y., Kleinsang, F., Schubert, M., Schwedhelm, E. & Guan, K. & 2 others, Wachter, R. & Böger, R., 3 Sept 2024, In: Journal of the American Heart Association. 13, 17, p. e034994 e034994.

Research output: Contribution to journal › Research article › Contributed › peer-review

Enhanced maturation of iPSC-CMs strongly improves their sensitivity to cardioactive drugs

Schubert, M., Li, W., Fischer, K., Pöche, J. & Guan, K., 1 Aug 2024. 1 p.

Research output: Contribution to conferences › Poster › Contributed

Gene therapy with phosphodiesterases 2A and 4B ameliorates heart failure and arrhythmias by improving subcellular cAMP compartmentation

Pavlaki, N., Froese, A., Li, W., De Jong, K. A., Geertz, B., Subramanian, H. & Mohagaonkar, S. & 10 others, Luo, X., Schubert, M., Wiegmann, R., Margaria, J. P., Ghigo, A., Kämmerer, S., Hirsch, E., El-Armouche, A., Guan, K. & Nikolaev, V. O., 1 Jun 2024, In: Cardiovascular research. 120, 9, p. 1011-1023 13 p.

Research output: Contribution to journal › Research article › Contributed › peer-review

View all research output (27)