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Dr. Mario Schubert
Person

Affiliations

Institute of Pharmacology and Toxicology
- Academic Staff
- mario.schubert1@tu-dresden.de

Research interests

Highly interested in molecular pharmacology and understaning molecular pathomechanisms of heart disease. In our research, we use iPSC-derived caridomyocytes as a human model system to study phsiology and pathophysiology by applying a variety of different methods including microphysiological cell culture chip systems, 3D tissue engineering and CRISPR-Cas9 genome editing.

Identification Numbers

ORCID	0000-0002-8375-8233
Scopus author ID	57210942570

Novel high-dense microelectrode array based multimodal bioelectronic monitoring system for cardiac arrhythmia re-entry analysis

Schmidt, S., Li, W., Schubert, M., Binnewerg, B., Prönnecke, C., Zitzmann, F. D., Bulst, M., & 4 othersWegner, S., Meier, M., Guan, K. & Jahnke, H. G., 15 May 2024, In: Biosensors and Bioelectronics. 252, 116120.

Research output: Contribution to journal › Research article › Contributed › peer-review

C-terminal variants in CDC42 drive type I interferon-dependent autoinflammation in NOCARH syndrome reversible by ruxolitinib

Kapp, F. G., Kretschmer, S., Beckmann, C. C. A., Wäsch, L., Molitor, A., Carapito, R., Schubert, M., & 25 othersLucas, N., Conrad, S., Poignant, S., Isidor, B., Rohlfs, M., Kisaarslan, A. P., Schanze, D., Zenker, M., Schmitt-Graeff, A., Strahm, B., Peters, A., Yoshimi, A., Driever, W., Zillinger, T., Günther, C., Maharana, S., Guan, K., Klein, C., Ehl, S., Niemeyer, C. M., Unal, E., Bahram, S., Hauck, F., Lee-Kirsch, M. A. & Speckmann, C., Nov 2023, In: Clinical immunology. 256, 109777.

Research output: Contribution to journal › Case report › Contributed › peer-review

CNP Promotes Antiarrhythmic Effects via Phosphodiesterase 2

Cachorro, E., Günscht, M., Schubert, M., Sadek, M. S., Siegert, J., Dutt, F., Bauermeister, C., & 18 othersQuickert, S., Berning, H., Nowakowski, F., Lämmle, S., Firneburg, R., Luo, X., Künzel, S. R., Klapproth, E., Mirtschink, P., Mayr, M., Dewenter, M., Vettel, C., Heijman, J., Lorenz, K., Guan, K., El-Armouche, A., Wagner, M. & Kämmerer, S., 17 Feb 2023, In: Circulation research. 132 (2023), 4, p. 400-414 15 p.

Research output: Contribution to journal › Research article › Contributed › peer-review

Synergistic Adverse Effects of Azithromycin and Hydroxychloroquine on Human Cardiomyocytes at a Clinically Relevant Treatment Duration

Li, W., Luo, X., Poetsch, M. S., Oertel, R., Nichani, K., Schneider, M., Strano, A., & 8 othersHasse, M., Steiner, R. P., Cyganek, L., Hettwer, K., Uhlig, S., Simon, K., Guan, K. & Schubert, M., Feb 2022, In: Pharmaceuticals. 15, 2, 24 p., 220.

Research output: Contribution to journal › Research article › Contributed › peer-review

Highly Selective Y<sub>4</sub> Receptor Antagonist Binds in an Allosteric Binding Pocket

Schüß, C., Vu, O., Schubert, M., Du, Y., Mishra, N. M., Tough, I. R., Stichel, J., & 5 othersWeaver, C., Emmitte, K., Cox, H. M., Meiler, J. & Beck-Sickinger, A., 11 Mar 2021, In: Journal of medicinal chemistry.

Research output: Contribution to journal › Research article › Contributed › peer-review

View all research output (20)

Advanced Maturation of iPSC-derived cardiomyocytes in 2D culture

Schubert, M. (Speaker)

25 Nov 2022

Activity: Talk or presentation at external institutions/events › Talk/Presentation › Invited

Oslo University Hospital

Schubert, M. (Visitor), Guan-Schmidt, K. (Visitor)

21 Sept 2022 → 23 Sept 2022

Activity: Visiting external institutions › Cooperations or projects

View all activities (2)

Etablierung eines humanen Multi-Organ-on-a-Chip Modells zur Untersuchung der Monozyten- und Makrophagenfunktion nach Ischämie-Reperfusionsschädigung

Schubert, Mario (Recipient), 20 Oct 2023

Prize: Fellow/scholarship › Other fellow/scholarship

View all prizes (4)

Metabolische Reifung und Charakterisierung von humanen künstlichen Herzmuskeln

Schubert, M.

5 Oct 2023

1 Media contribution

Press/Media

View all press/media (1)

Research Portal of the TU Dresden

Dr. Mario Schubert
Person

Affiliations

Research interests

Identification Numbers

Related content

Novel high-dense microelectrode array based multimodal bioelectronic monitoring system for cardiac arrhythmia re-entry analysis

C-terminal variants in CDC42 drive type I interferon-dependent autoinflammation in NOCARH syndrome reversible by ruxolitinib

CNP Promotes Antiarrhythmic Effects via Phosphodiesterase 2

Synergistic Adverse Effects of Azithromycin and Hydroxychloroquine on Human Cardiomyocytes at a Clinically Relevant Treatment Duration

Highly Selective Y<sub>4</sub> Receptor Antagonist Binds in an Allosteric Binding Pocket

Advanced Maturation of iPSC-derived cardiomyocytes in 2D culture

Oslo University Hospital

Etablierung eines humanen Multi-Organ-on-a-Chip Modells zur Untersuchung der Monozyten- und Makrophagenfunktion nach Ischämie-Reperfusionsschädigung

MeDDrive Grant 2022

MeDDrive Start Grant

Max-Kade Fellowship

Metabolische Reifung und Charakterisierung von humanen künstlichen Herzmuskeln