Evaluation of semipermeable membranes for encapsulating gas sensors in human intestinal environments

Research output: Contribution to book/conference proceedings/anthology/reportConference contributionContributedpeer-review

Abstract

This work describes a comparison of biocompatible membranes to encapsulate gas sensors in the human intestinal tract. The goal is to identify semipermeable materials that allow intestinal gases to pass through the membrane while also separating them from other intestinal contents. Important aspects of this study are the membranes’ chemical resistance to gastric acid and their gas permeability. Chemical resistance was assessed by submerging selected membranes in artificial gastric acid. Surface structure of membrane samples before and after the acid treatment was compared using scanning electron microscopy and signs of degradation were documented. To characterize the membranes in terms of their gas permeability, an experimental setup was developed to measure average airflow through the membranes. A constant pressure of 7 kPa was applied across the membrane and flow rate Q of air was measured over a predefined surface area A. This evaluation marks the first step in the development of an ingestible capsule for in-vivo analysis of intestinal gases.

Details

Original languageGerman
Title of host publication2024 47th International Spring Seminar on Electronics Technology (ISSE)
PublisherIEEE
Pages1-4
Number of pages4
Volume2024
ISBN (electronic)9798350385472
ISBN (print)979-8-3503-8548-9
Publication statusPublished - 19 May 2024
Peer-reviewedYes

Conference

Title2024 47th International Spring Seminar on Electronics Technology (ISSE)
Duration15 - 19 May 2024
LocationPrague, Czech Republic

External IDs

ORCID /0000-0002-0757-3325/work/165062953
Scopus 85200480012

Keywords

Keywords

  • Biomembranes, Degradation, Gases, Permeability, Sensors, Surface structures, Water