A Tug-of-War between Cell Shape and Polarity Controls Division Orientation to Ensure Robust Patterning in the Mouse Blastocyst
Research output: Contribution to journal › Research article › Contributed › peer-review
Contributors
Abstract
Based on systematic characterization of cell division, volume, and shape changes by in toto imaging, Niwayama et al. propose a model in which a tug-of-war between cell shape and the apical domain determines division orientation to ensure robust cell allocation and patterning in mouse pre-implantation embryos.
Details
| Original language | English |
|---|---|
| Pages (from-to) | 564-574.e6 |
| Journal | Developmental cell |
| Volume | 51 |
| Issue number | 5 |
| Publication status | Published - 2 Dec 2019 |
| Peer-reviewed | Yes |
External IDs
| PubMed | 31735668 |
|---|
Keywords
ASJC Scopus subject areas
Keywords
- cell polarity, cell shape, division orientation, embryo patterning, mouse embryos, self-organization