University Cancer Centre Dresden, Medical Systems Biology

Organisational unit: Chair

Organisation profile

Systems biology and genome engineering are at the forefront of transforming our healthcare system. The Department of Medical Systems Biology at the University Cancer Center of TU Dresden integrates functional genomics, high-throughput biology and genome editing to transform precision medicine.

Contact

Type of address: Visiting Adress.

BIOTEC
Medical Systems Biology, Prof. Dr. Frank Buchholz
Tatzberg 47/49
01307 Dresden

Germany

Type of address: Postal address.

UCC, Medical Systems Biology
Prof. Dr. Frank Buchholz
Medizinische Fakultät, TU Dresden
Fetscherstr. 74
01307 Dresden

Germany

Phone: 0351-46340274

Email: buchholz-office@groups.tu-dresden.de

Other website: http://www.buchholzlab.org/
TUD website: https://tu-dresden.de/med/mf/ucc/medsys?set_language=en

Parent units

University Cancer Centre Dresden

Activation of recombinases at specific DNA loci by zinc-finger domain insertions

Mukhametzyanova, L., Schmitt, L. T., Torres-Rivera, J., Rojo-Romanos, T., Lansing, F., Paszkowski-Rogacz, M. & Hollak, H. & 4 others, Brux, M., Augsburg, M., Schneider, P. M. & Buchholz, F., Dec 2024, In: Nature biotechnology. 42, 12, p. 1844-1854 11 p.

Research output: Contribution to journal › Research article › Contributed › peer-review

Non-viral vectors for chimeric antigen receptor immunotherapy

Tretbar, U. S., Rurik, J. G., Rustad, E. H., Sürün, D., Köhl, U., Olweus, J. & Buchholz, F. & 3 others, Ivics, Z., Fricke, S. & Blache, U., Dec 2024, In: Nature Reviews Methods Primers. 4, 1, 74.

Research output: Contribution to journal › Research article › Contributed › peer-review

Characterization of immortalized bone marrow erythroid progenitor adult (imBMEP-A)—The first inducible immortalized red blood cell progenitor cell line derived from bone marrow CD71-positive cells

Kronstein-Wiedemann, R., Thiel, J., Sürün, D., Teichert, M., Künzel, S. R., Zimmermann, S. & Wagenführ, L. & 2 others, Buchholz, F. & Tonn, T., Nov 2024, In: Cytotherapy. 26, 11, p. 1362-1373 12 p.

Research output: Contribution to journal › Research article › Contributed › peer-review

Selective regulation of aspartyl intramembrane protease activity by calnexin

Contreras, W. (First author), Groenendyk, J., Gentzel, M., Schönberg, P. Y., Buchholz, F., Michalak, M. & Schröder, B. & 1 others, Mentrup, T. (Last author), 26 Oct 2024, In: Cellular and Molecular Life Sciences. 81, 1, 17 p., 441.

Research output: Contribution to journal › Research article › Contributed › peer-review

Immunotherapeutic Targeting of Glioblastoma Using Switchable Adaptor RevCAR T- and NK-92-Cell Platforms

Saleh Hassan, H., 25 Sept 2024, 166 p.

Research output: Types of thesis › Doctoral thesis

View all research output (143)

Krankenhauspharmazie

ISSNs: 0173-7597

Additional searchable ISSN (electronic): 0173-7597

Deutscher Apotheker Verlag, Germany

Scopus rating (2023): CiteScore 0.1 SJR 0.138 SNIP 0.122

Journal

Nature Reviews. Methods Primers

Additional searchable ISSN (electronic): 2662-8449

Springer Nature, United Kingdom

Scopus rating (2023): CiteScore 46.1 SJR 12.294 SNIP 13.074

Journal

GEN : genetic engineering & biotechnology news ; biotechnology from bench to business

ISSNs: 0270-6377

Additional searchable ISSN (electronic): 1937-8661

Mary Ann Liebert Publishers, Larchmont, United States of America

Journal

Cellular oncology : the official journal of the International Society for Cellular Oncology

ISSNs: 2211-3428

Additional searchable ISSN (electronic): 2211-3436

Springer Science and Business Media B.V., Germany

Buchholz, F. (Speaker)

20 Jun 2024

Activity: Talk or presentation at external institutions/events › Talk/Presentation › Invited

View all activities (176)

Dr. Walter Seipp-Preis of the Commerzbank Foundation

Mukhametzyanova, L. (Recipient), 27 Oct 2024

Prize: Other prize

Buchholz, F.

30 Jun 2023

1 item of Media coverage

Press/Media

View all press/media (9)

Research Portal of the TU Dresden

University Cancer Centre Dresden, Medical Systems Biology

Organisation profile

Contact

Parent units

Related content and researchers (public profile)

Activation of recombinases at specific DNA loci by zinc-finger domain insertions

Non-viral vectors for chimeric antigen receptor immunotherapy

Characterization of immortalized bone marrow erythroid progenitor adult (imBMEP-A)—The first inducible immortalized red blood cell progenitor cell line derived from bone marrow CD71-positive cells

Selective regulation of aspartyl intramembrane protease activity by calnexin

Immunotherapeutic Targeting of Glioblastoma Using Switchable Adaptor RevCAR T- and NK-92-Cell Platforms

Krankenhauspharmazie

Nature Reviews. Methods Primers

GEN : genetic engineering & biotechnology news ; biotechnology from bench to business

Cellular oncology : the official journal of the International Society for Cellular Oncology

Krebs im Focus : die Wissenschaftszeitschrift des UniversitätsKrebsCentrums Dresden / UCC

DG-GT Annual Meeting 2025

FVIII intron 1 inversion editing

Engineering Designer-Recombinases for therapeutic genome editing

Engineering designer-recombinases for therapeutic genome editing

Engineering Designer-Recombinases for Therapeutic Genome Editing

Dr. Walter Seipp-Preis of the Commerzbank Foundation

Immunotherapeutic targeting of glioblastoma using Fn14-redirected RevCAR effector cells; Immuntherapeutische Behandlung von Glioblastomen mit Fn14-gesteuerten RevCAR-Effektorzellen

DRESDEN EXCELENCE AWARD

UNIPRENEURS chair

DRESDEN EXCELLENCE AWARD

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