INSTALLing recombinase-driven genome writing: Engineered single-stranded donors bypass innate immunity to enable large DNA integration
Research output: Contribution to journal › Letter › Contributed › peer-review
Contributors
Abstract
In a recent Nature article, Tou et al. 1 introduce INSTALL, a strategy that couples immune-evasive circular single-stranded DNA (cssDNA) technology with recombinase-based genome editing to overcome innate immune barriers and enable the integration of large DNA cargos.
Details
| Original language | English |
|---|---|
| Pages (from-to) | 1836-1838 |
| Number of pages | 3 |
| Journal | Molecular cell |
| Volume | 86 |
| Issue number | 10 |
| Publication status | Published - 21 May 2026 |
| Peer-reviewed | Yes |