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Porf. Dr. phil. Mareike Albert

Person

Research interests

The neocortex is considered to be the seat of higher cognitive functions in humans. During its evolution, most notably in humans, the neocortex has undergone considerable expansion, which is reflected by an increase in the number of neurons. Neocortical neurons are generated during development by neural stem and progenitor cells. Epigenetic mechanisms play a pivotal role in orchestrating the behavior of stem cells during development. We are interested in the mechanisms that regulate gene expression in neural stem cells, which have implications for our understanding of neocortex development and evolution, neural stem cell regulation and neurodevelopmental diseases.

Career

2018-2013PostDoc, Max Planck Institute of Molecular Cell Biology and Genetics, external link
2012-2008Postdoc, Biotech Research and Innovation Centre, external link
2008-2004PhD student, Friedrich Miescher Institute, external link
2003-2002Intern, Curtin University, external link

 

Identification Numbers

ORCID Orcid 0000-0001-9855-9344, external link
Scopus author ID 26532449500

Related content

Electroporation of Sliced Human Cortical Organoids for Studies of Gene Function

Kolodziejczyk, A., Hoffmann, J., Cubillos, P. & Albert, M., 29 Nov 2024, In: Journal of visualized experiments : JoVE. 213, e67598.

Research output: Contribution to journal › Research article › Contributed › peer-review

Epigenome profiling identifies H3K27me3 regulation of extra-cellular matrix composition in human corticogenesis

Ditzer, N., Şenoğlu, E., Schütze, T. M., Nikolaidi, A., Kolodziejczyk, A., Sameith, K. & Dietz, S. & 9 others, Derihaci, R. P., Birdir, C., Eugster, A., Karl, M. O., Dahl, A., Wimberger, P., Baenke, F., Peitzsch, C. & Albert, M., 2 Oct 2024.

Research output: Preprint/Documentation/Report › Preprint

Canonical and non-canonical PRC1 differentially contribute to the regulation of neural stem cell fate

Hoffmann, J., Schütze, T. M., Kolodziejczyk, A., Kränkel, A., Reinhardt, S., Derihaci, R. P. & Birdir, C. & 3 others, Wimberger, P., Koseki, H. & Albert, M., 7 Aug 2024.

Research output: Preprint/Documentation/Report › Preprint

The growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortex

Cubillos, P., Ditzer, N., Kolodziejczyk, A., Schwenk, G., Hoffmann, J., Schütze, T. M. & Derihaci, R. P. & 8 others, Birdir, C., Köllner, J. E. M., Petzold, A., Sarov, M., Martin, U., Long, K. R., Wimberger, P. & Albert, M., 16 Apr 2024, In: EMBO Journal. 43(2024), 8, p. 1388-1419 32 p.

Research output: Contribution to journal › Research article › Contributed › peer-review

Joint epigenome profiling reveals cell-type-specific gene regulatory programmes in human cortical organoids

Noack, F., Vangelisti, S., Ditzer, N., Chong, F., Albert, M. & Bonev, B., Dec 2023, In: Nature cell biology. 25, 12, p. 1873-1883 11 p.

Research output: Contribution to journal › Research article › Contributed › peer-review

View all research output (30)