Technical recommendations for analyzing oxylipins by liquid chromatography-mass spectrometry

Research output: Contribution to journal › Research article › Contributed › peer-review

Contributors

  • Nils Helge Schebb - , University of Wuppertal (Author)
  • Nadja Kampschulte - , University of Wuppertal (Author)
  • Gerhard Hagn - , Karolinska Institutet (Author)
  • Kathrin Plitzko - , University of Wuppertal (Author)
  • Sven W. Meckelmann - , University of Duisburg-Essen (Author)
  • Soumita Ghosh - , University of Pennsylvania Perelman School of Medicine (Author)
  • Robin Joshi - , University of Pennsylvania Perelman School of Medicine (Author)
  • Julia Kuligowski - , University of Valencia (Author)
  • Dajana Vuckovic - , Concordia University (Author)
  • Marina T. Botana - , Karolinska Institutet, Victoria University of Wellington (Author)
  • Ángel Sánchez-Illana - , University of Valencia (Author)
  • Fereshteh Zandkarimi - , Columbia University (Author)
  • Aditi Das - , Georgia Institute of Technology (Author)
  • Jun Yang - , University of California at Davis (Author)
  • Louis Schmidt - , University of Greifswald (Author)
  • Antonio Checa - , Karolinska Institutet (Author)
  • Helen M. Roche - , University College Dublin, Queen's University Belfast (Author)
  • Aaron M. Armando - , University of California at San Diego (Author)
  • Matthew L. Edin - , National Institutes of Health (NIH) (Author)
  • Fred B. Lih - , National Institutes of Health (NIH) (Author)
  • Juan J. Aristizabal-Henao - , BPGbio, Inc. (Author)
  • Sayuri Miyamoto - , Universidade de São Paulo (Author)
  • Francesca Giuffrida - , Nestle (Author)
  • Arieh Moussaieff - , Hebrew University of Jerusalem (Author)
  • Rosário Domingues - , University of Aveiro (Author)
  • Michael Rothe - , Lipidomix GmbH (Author)
  • Christine Hinz - , Shimadzu UK Limited (Author)
  • Ujjalkumar Subhash Das - , University of Pennsylvania Perelman School of Medicine (Author)
  • Katharina M. Rund - , University of Wuppertal (Author)
  • Ameer Y. Taha - , University of California at Davis (Author)
  • Robert K. Hofstetter - , Friedrich Schiller University Jena (Author)
  • Markus Werner - , Friedrich Schiller University Jena (Author)
  • Oliver Werz - , Friedrich Schiller University Jena (Author)
  • Astrid S. Kahnt - , Goethe University Frankfurt a.M. (Author)
  • Justine Bertrand-Michel - , Institute of Metabolic and Cardiovascular Diseases (I2MC) (Author)
  • Pauline Le Faouder - , Institute of Metabolic and Cardiovascular Diseases (I2MC) (Author)
  • Robert Gurke - , University Hospital Frankfurt, Fraunhofer Institute for Translational Medicine and Pharmacology, Fraunhofer Cluster of Excellence Immune-Mediated Diseases (Author)
  • Dominique Thomas - , University Hospital Frankfurt, Fraunhofer Institute for Translational Medicine and Pharmacology, Fraunhofer Cluster of Excellence Immune-Mediated Diseases (Author)
  • Federico Torta - , National University of Singapore (Author)
  • Ivana Milic - , Aston University (Author)
  • Irundika H.K. Dias - , Aston University (Author)
  • Corinne M. Spickett - , Aston University (Author)
  • Denise Biagini - , University of Pisa (Author)
  • Tommaso Lomonaco - , University of Pisa (Author)
  • Helena Idborg - , Karolinska Institutet (Author)
  • Jun Yan Liu - , Chongqing Medical University (Author)
  • Maria Fedorova - , Center of Membrane Biochemistry and Lipid Research (Author)
  • David A. Ford - , Saint Louis University (Author)
  • Anne Barden - , University of Western Australia (Author)
  • Trevor A. Mori - , University of Western Australia (Author)
  • Paul D. Kennedy - , Cayman Chemical (Author)
  • Kirk Maxey - , Cayman Chemical (Author)
  • Julijana Ivanisevic - , University of Lausanne (Author)
  • Hector Gallart-Ayala - , University of Lausanne (Author)
  • Cécile Gladine - , INRAE - National Institute of Agricultural Research (Author)
  • Markus Wenk - , Hamad bin Khalifa University, National University of Singapore (Author)
  • Jean Marie Galano - , Institut des Biomolécules Max Mousseron (Author)
  • Thierry Durand - , Institut des Biomolécules Max Mousseron (Author)
  • Ken D. Stark - , University of Waterloo (Author)
  • Coral Barbas - , CEU San Pablo University (Author)
  • Ulrike Garscha - , University of Greifswald (Author)
  • Stacy L. Gelhaus - , University of Pittsburgh (Author)
  • Uta Ceglarek - , Leipzig University (Author)
  • Nicolas Flamand - , Université Laval (Author)
  • Julian L. Griffin - , University of Aberdeen (Author)
  • Robert Ahrends - , University of Vienna (Author)
  • Makoto Arita - , RIKEN Center for Integrative Medical Sciences (Author)
  • Darryl C. Zeldin - , National Institutes of Health (NIH) (Author)
  • Francisco J. Schopfer - , University of Pittsburgh (Author)
  • Oswald Quehenberger - , University of California at San Diego (Author)
  • Randall Julian - , Indigo BioAutomation, Inc. (Author)
  • Anna Nicolaou - , University of Manchester (Author)
  • Ian A. Blair - , University of Pennsylvania (Author)
  • Michael P. Murphy - , Medical Research Council (MRC) (Author)
  • Bruce D. Hammock - , University of California at Davis (Author)
  • Bruce Freeman - , University of Pittsburgh (Author)
  • Gerhard Liebisch - , University of Regensburg (Author)
  • Charles N. Serhan - , Harvard University (Author)
  • Harald C. Köfeler - , Medical University of Graz (Author)
  • Per Johan Jakobsson - , Karolinska Institutet (Author)
  • Dieter Steinhilber - , Goethe University Frankfurt a.M. (Author)
  • Michael H. Gelb - , University of Washington (Author)
  • Michal Holčapek - , University of Pardubice (Author)
  • Ruth Andrew - , University of Edinburgh (Author)
  • Martin Giera - , Leiden University (Author)
  • Garret A. FitzGerald - , University of Pennsylvania Perelman School of Medicine (Author)
  • Robert C. Murphy - , University of Colorado Denver (Author)
  • John W. Newman - , University of California at Davis (Author)
  • Edward A. Dennis - , University of California at San Diego (Author)
  • Kim Ekroos - , Lipidomics Consulting Ltd. (Author)
  • Ginger L. Milne - , Vanderbilt University Medical Center (Author)
  • Miguel A. Gijón - , Cayman Chemical (Author)
  • Hubert W. Vesper - , Centers for Disease Control and Prevention (Author)
  • Craig E. Wheelock - , Karolinska Institutet (Author)
  • Valerie B. O'Donnell - , Cardiff University (Author)

Abstract

Several oxylipins are potent lipid mediators that regulate diverse aspects of health and disease and whose quantitative analysis by liquid chromatography-mass spectrometry (LC-MS) presents substantial technical challenges. As members of the lipidomics community, we developed technical recommendations to ensure best practices when quantifying oxylipins by LC-MS.

Details

Original languageEnglish
Article numbereadw1245
JournalScience signaling
Volume18
Issue number887
Publication statusPublished - 20 May 2025
Peer-reviewedYes

External IDs

Scopus 105006531246
PubMed 40392938

Keywords