Studies of a proton bunch phase monitor for range verification in proton therapy

Research output: Contribution to book/conference proceedings/anthology/reportConference contributionContributed

Contributors

Abstract

A primary subject of the present research in particle therapy is to ensure the precise irradiation of the target volume. The prompt gamma timing (PGT) method provides one possibility for in vivo range verification during the irradiation of patients. Prompt gamma rays with high energies are emitted promptly due to nuclear reactions of protons with tissue. The arrival time of these gammas to the detector reflects the stopping process of the primary protons in tissue and is directly correlated to the range. Due to the time resolution of the detector and the proton bunch time spread, as well as drifts of the bunch phase with respect to the accelerator frequency, timing spectra are smeared out and compromise the accuracy of range information intended for future clinical applications. Nevertheless, counteracting this limitation and recovering range information from the PGT measured spectra, corrections using a bunch phase monitor can be performed. A first prototype of bunch phase monitor was tested at GSI Darmstadt, where measurements of the energy correlation profile of the ion bunches were performed. At the ELBE accelerator at Helmholtz-Zentrum Dresden-Rossendorf (HZDR), set up to provide bremsstrahlung photons in very short pulses, a constant fraction algorithm for the incoming digital signals was evaluated, which is used for optimizing the time resolution. Studies of scattering experiments with different thin targets and detector positions are accomplished at OncoRay Dresden, where a clinical proton beam is available. These experiments allow a basic characterization of the proton bunch structure and the detection yield.

Details

Original languageEnglish
Title of host publication2015 4th International Conference on Advancements in Nuclear Instrumentation Measurement Methods and their Applications (ANIMMA)
PublisherIEEE Computational Intelligence Society (CIS)
Pages1-6
Number of pages6
ISBN (print)978-1-4799-9917-0
Publication statusPublished - 24 Apr 2015
Peer-reviewedNo

Conference

Title2015 4th International Conference on Advancements in Nuclear Instrumentation Measurement Methods and their Applications
Abbreviated titleANIMMA 2015
Conference number4
Duration20 - 24 April 2015
LocationLisbon Congress Center
CityLisbon
CountryPortugal

External IDs

Scopus 84974628152
ORCID /0000-0001-9023-3606/work/142252766

Keywords

Keywords

  • Protons, Detectors, Timing, Particle beams, Energy measurement, Photonics, Atmospheric measurements