Studies of a proton bunch phase monitor for range verification in proton therapy

Publikation: Beitrag in Buch/Konferenzbericht/Sammelband/GutachtenBeitrag in KonferenzbandBeigetragen

Beitragende

Abstract

A primary subject of the present research in particle therapy is to ensure the precise irradiation of the target volume. The prompt gamma timing (PGT) method provides one possibility for in vivo range verification during the irradiation of patients. Prompt gamma rays with high energies are emitted promptly due to nuclear reactions of protons with tissue. The arrival time of these gammas to the detector reflects the stopping process of the primary protons in tissue and is directly correlated to the range. Due to the time resolution of the detector and the proton bunch time spread, as well as drifts of the bunch phase with respect to the accelerator frequency, timing spectra are smeared out and compromise the accuracy of range information intended for future clinical applications. Nevertheless, counteracting this limitation and recovering range information from the PGT measured spectra, corrections using a bunch phase monitor can be performed. A first prototype of bunch phase monitor was tested at GSI Darmstadt, where measurements of the energy correlation profile of the ion bunches were performed. At the ELBE accelerator at Helmholtz-Zentrum Dresden-Rossendorf (HZDR), set up to provide bremsstrahlung photons in very short pulses, a constant fraction algorithm for the incoming digital signals was evaluated, which is used for optimizing the time resolution. Studies of scattering experiments with different thin targets and detector positions are accomplished at OncoRay Dresden, where a clinical proton beam is available. These experiments allow a basic characterization of the proton bunch structure and the detection yield.

Details

OriginalspracheEnglisch
Titel2015 4th International Conference on Advancements in Nuclear Instrumentation Measurement Methods and their Applications (ANIMMA)
Herausgeber (Verlag)IEEE Computational Intelligence Society (CIS)
Seiten1-6
Seitenumfang6
ISBN (Print)978-1-4799-9917-0
PublikationsstatusVeröffentlicht - 24 Apr. 2015
Peer-Review-StatusNein

Konferenz

Titel2015 4th International Conference on Advancements in Nuclear Instrumentation Measurement Methods and their Applications
KurztitelANIMMA 2015
Veranstaltungsnummer4
Dauer20 - 24 April 2015
OrtLisbon Congress Center
StadtLisbon
LandPortugal

Externe IDs

Scopus 84974628152
ORCID /0000-0001-9023-3606/work/142252766

Schlagworte

Schlagwörter

  • Protons, Detectors, Timing, Particle beams, Energy measurement, Photonics, Atmospheric measurements