The paper presents the fabrication and implementation of highly flexible graphene/PEDOT:PSS composite-based sensors. While there is a huge demand for printable low-cost sensors for strain-induced applications, graphene composites are a remarkable benchmark due to their high robustness and mechanical integrity. These nanocomposites have been mixed with various polymers to develop sensors for human motion. The presence of conductive polymers like poly(3,4-ethylenedioxythiophene):poly(styrene-sulfonate) (PEDOT:PSS) in the graphene sensor has shown compelling performance in terms of sensitivity and longevity. The electromechanical characterization of the sensors highlighted their efficient performance under widely applied pressure ranges. Additionally, sponge substrates have allowed the detection of physiological movements when used on a graphic user interface (GUI)-embedded human glove. These prototypes have displayed significant performance of sponge-based flexible electronic systems to detect fine and gross strain-induced movements.