Morphology of bony tissues and implants uncovered by high-resolution tomographic imaging

Research output: Contribution to journalResearch articleContributedpeer-review


  • Bert Müller - , University of Basel (Author)
  • Ricardo Bernhardt - , Chair of Biomaterials, Max Bergmann Center of Biomaterials Dresden (Author)
  • Timm Weitkamp - , Karlsruhe Institute of Technology (Author)
  • Felix Beckmann - , Helmholtz-Zentrum Hereon (Author)
  • Rolf Bräuer - , Friedrich Schiller University Jena (Author)
  • Uta Schurigt - , Friedrich Schiller University Jena (Author)
  • Annelies Schrott-Fischer - , Innsbruck Medical University (Author)
  • Rudolf Glueckert - , Innsbruck Medical University (Author)
  • Michael Ney - , Department of Otorhinolaryngology, Head and Neck Surgery (Author)
  • Thomas Beleites - , Department of Otorhinolaryngology, Head and Neck Surgery (Author)
  • Claude Jolly - , MED-EL GmbH (Author)
  • Dieter Scharnweber - , Chair of Biomaterials, Max Bergmann Center of Biomaterials Dresden (Author)


Synchrotron radiation-based micro computed tomography contributes to the increasing demand for uncovering nondestructively the microscopic morphology of bony tissues and their interface regions with implants using isotropic spatial resolution in three-dimensional space. Using the microscopic ring structure of otoliths, the coherence-related interplay between density resolution and spatial resolution is demonstrated. The monochromatised, highly intense synchrotron radiation allows analysis of the morphology of arthritic joints without significant beam-hardening artefacts in a quantitative manner. It further enables intensity-based segmentation of metallic implants within bone and thereby to quantitatively study the bone morphology around different kinds of middle and inner ear implants. This knowledge permits improving medical interventions and optimising the implant's design with respect to surface modification, mechanical properties, and shape.


Original languageEnglish
Pages (from-to)613-621
Number of pages9
JournalInternational Journal of Materials Research
Issue number7
Publication statusPublished - Jul 2007



  • Cochlea, Hard tissue, Implant, Otolith, Synchrotron radiation tomography