Morphology of bony tissues and implants uncovered by high-resolution tomographic imaging

Publikation: Beitrag in FachzeitschriftForschungsartikelBeigetragenBegutachtung


  • Bert Müller - , Universität Basel (Autor:in)
  • Ricardo Bernhardt - , Professur für Biomaterialien, Max Bergmann Zentrum für Biomaterialien Dresden (MBZ) (Autor:in)
  • Timm Weitkamp - , Karlsruhe Institute of Technology (Autor:in)
  • Felix Beckmann - , Helmholtz-Zentrum Hereon (Autor:in)
  • Rolf Bräuer - , Friedrich-Schiller-Universität Jena (Autor:in)
  • Uta Schurigt - , Friedrich-Schiller-Universität Jena (Autor:in)
  • Annelies Schrott-Fischer - , Medizinische Universität Innsbruck (Autor:in)
  • Rudolf Glueckert - , Medizinische Universität Innsbruck (Autor:in)
  • Michael Ney - , Klinik und Poliklinik für Hals-Nasen-Ohrenheilkunde (Autor:in)
  • Thomas Beleites - , Klinik und Poliklinik für Hals-Nasen-Ohrenheilkunde (Autor:in)
  • Claude Jolly - , MED-EL GmbH (Autor:in)
  • Dieter Scharnweber - , Professur für Biomaterialien, Max Bergmann Zentrum für Biomaterialien Dresden (MBZ) (Autor:in)


Synchrotron radiation-based micro computed tomography contributes to the increasing demand for uncovering nondestructively the microscopic morphology of bony tissues and their interface regions with implants using isotropic spatial resolution in three-dimensional space. Using the microscopic ring structure of otoliths, the coherence-related interplay between density resolution and spatial resolution is demonstrated. The monochromatised, highly intense synchrotron radiation allows analysis of the morphology of arthritic joints without significant beam-hardening artefacts in a quantitative manner. It further enables intensity-based segmentation of metallic implants within bone and thereby to quantitatively study the bone morphology around different kinds of middle and inner ear implants. This knowledge permits improving medical interventions and optimising the implant's design with respect to surface modification, mechanical properties, and shape.


Seiten (von - bis)613-621
FachzeitschriftInternational Journal of Materials Research
PublikationsstatusVeröffentlicht - Juli 2007



  • Cochlea, Hard tissue, Implant, Otolith, Synchrotron radiation tomography