Model-based Comparison of Cell Density-dependent Cell Migration Strategies

Research output: Contribution to journalResearch articleContributedpeer-review

Abstract

Here, we investigate different cell density-dependent migration strategies. In particular, we consider strategies which differ in the precise regulation of transitions between resting and motile phenotypes. We develop a lattice-gas cellular automaton (LGCA) model for each migration strategy. Using a mean-field approximation we quantify the corresponding spreading dynamics at the cell population level. Our results allow for the prediction of cell population spreading based on experimentally accessible single cell migration parameters.

Details

Original languageEnglish
Number of pages14
Journal Mathematical modelling of natural phenomena : MMNP
Volume10
Issue number1
Publication statusPublished - 2015
Peer-reviewedYes

External IDs

Scopus 84922875647
ORCID /0000-0002-1270-7885/work/211721176

Keywords