Model-based Comparison of Cell Density-dependent Cell Migration Strategies

Publikation: Beitrag in FachzeitschriftForschungsartikelBeigetragenBegutachtung

Abstract

Here, we investigate different cell density-dependent migration strategies. In particular, we consider strategies which differ in the precise regulation of transitions between resting and motile phenotypes. We develop a lattice-gas cellular automaton (LGCA) model for each migration strategy. Using a mean-field approximation we quantify the corresponding spreading dynamics at the cell population level. Our results allow for the prediction of cell population spreading based on experimentally accessible single cell migration parameters.

Details

OriginalspracheEnglisch
Seitenumfang14
Fachzeitschrift Mathematical modelling of natural phenomena : MMNP
Jahrgang10
Ausgabenummer1
PublikationsstatusVeröffentlicht - 2015
Peer-Review-StatusJa

Externe IDs

Scopus 84922875647
ORCID /0000-0002-1270-7885/work/211721176

Schlagworte