Microfluidic detection module for DNA analysis using integrated microheaters and DNA microarrays on plastic foil
Research output: Contribution to book/Conference proceedings/Anthology/Report › Conference contribution › Contributed › peer-review
Contributors
Abstract
We report detection of single nucleotide polymorphisms (SNP) by melting curve analysis (MCA) on DNA microarrays in a plastic microfluidic system with integrated heaters using lamination foils. Thin-film copper microheaters were structured on polyethylene napthalate (PEN) foil and DNA microarrays were printed on the heater foil. The system was integrated in a microfluidic channel and successful detection of SNPs was demonstrated. Thermal and electrical characterization of the system was performed proving that the recently implemented low-cost heater encapsulation method using a simple single-sided adhesive foil has not affected the systems performance relative the previous Parylene C encapsulation.
Details
Original language | English |
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Title of host publication | Sensoren und Messsysteme 2014 - 17. ITG/GMA-Fachtagung |
Publisher | VDE Verlag, Berlin [u. a.] |
ISBN (electronic) | 9783800736225 |
Publication status | Published - 2013 |
Peer-reviewed | Yes |
Publication series
Series | Sensoren und Messsysteme 2014 - 17. ITG/GMA-Fachtagung |
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Symposium
Title | 17th ITG/GMA Conference on Sensors and Measuring Systems 2014 |
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Subtitle | Sensoren und Messsysteme 2014 |
Abbreviated title | Sensoren2014 |
Conference number | 17 |
Duration | 3 - 4 June 2014 |
Degree of recognition | National event |
Location | Convention Center |
City | Nürnberg |
Country | Germany |
External IDs
ORCID | /0000-0002-0757-3325/work/139064936 |
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