Is Protein BLAST a thing of the past?

Ali Al-Fatlawi; Martin Menzel; Michael Schroeder

doi:10.1038/s41467-023-44082-5

Is Protein BLAST a thing of the past?

Research output: Contribution to journal › Comment/Debate › Contributed › peer-review

Contributors

Ali Al-Fatlawi - , Biotechnology Center, Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI Dresden), Chair of Bioinformatics (Author)
Martin Menzel - , Biotechnology Center (BIOTEC) (Author)
Michael Schroeder - , Chair of Bioinformatics, Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI Dresden) (Author)

Abstract

Will protein structure search tools like AlphaFold replace protein sequence search with BLAST? We discuss the promises, using structure search for remote homology detection, and why protein BLAST, as the leading sequence search tool, should strive to incorporate structural information

Details

Original language	English
Article number	8195
Journal	Nature communications
Volume	14
Issue number	1
Publication status	Published - 11 Dec 2023
Peer-reviewed	Yes

External IDs

unpaywall	10.1038/s41467-023-44082-5
Scopus	85179345951
ORCID	/0000-0003-2848-6949/work/173987743

Research Portal of the TU Dresden

Is Protein BLAST a thing of the past?

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Abstract

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