International consensus statement on the diagnosis and management of phaeochromocytoma and paraganglioma in children and adolescents

Research output: Contribution to journalReview articleContributedpeer-review

Contributors

  • Ruth T Casey - , Cambridge University Hospitals NHS Foundation Trust (Author)
  • Emile Hendriks - , Cambridge University Hospitals NHS Foundation Trust (Author)
  • Cheri Deal - , University Hospital Centre Sainte-Justine (CHUSJ) (Author)
  • Steven G Waguespack - , University of Texas MD Anderson Cancer Center (Author)
  • Verena Wiegering - , University Hospital of Würzburg (Author)
  • Antje Redlich - , University Hospital Magdeburg (Author)
  • Scott Akker - , Barts Health NHS Trust (Author)
  • Rathi Prasad - , Queen Mary University of London (Author)
  • Martin Fassnacht - , University Hospital of Würzburg (Author)
  • Roderick Clifton-Bligh - , Royal North Shore Hospital (Author)
  • Laurence Amar - , Assistance publique – Hôpitaux de Paris (Author)
  • Stefan Bornstein - , Department of Internal Medicine III, University Hospital Carl Gustav Carus Dresden (Author)
  • Letizia Canu - , Careggi University Hospital (Author)
  • Evangelia Charmandari - , National and Kapodistrian University of Athens, Agia Sofia Children's Hospital, Athens (Author)
  • Alexandra Chrisoulidou - , Theagenio Cancer Hospital (Author)
  • Maria Currás Freixes - , CIBER - Center for Biomedical Research Network, Instituto de Salud Carlos III (Author)
  • Ronald de Krijger - , University Medical Center (UMC) Utrecht (Author)
  • Luisa de Sanctis - , University of Turin (Author)
  • Antonio Fojo - , Columbia University Irving Medical Center (CUMC) (Author)
  • Amol J Ghia - , University of Texas MD Anderson Cancer Center (Author)
  • Angela Huebner - , Department of Paediatrics (Author)
  • Vasilis Kosmoliaptsis - , National Institute for Health Research (NIHR), University of Cambridge (Author)
  • Michaela Kuhlen - , University Hospital Augsburg (Author)
  • Marco Raffaelli - , Catholic University of the Sacred Heart (Author)
  • Charlotte Lussey-Lepoutre - , Pitié-Salpêtrière Hospital, Sorbonne Université (Author)
  • Stephen D Marks - , Great Ormond Street Hospital for Children NHS Trust, University College London (Author)
  • Naris Nilubol - , National Institutes of Health (NIH) (Author)
  • Mirko Parasiliti-Caprino - , University of Turin (Author)
  • Henri H J L M Timmers - , Radboud University Medical Center (Author)
  • Anna Lena Zietlow - , Chair of Clinical Child and Adolescent Psychology (Author)
  • Mercedes Robledo - , CIBER - Center for Biomedical Research Network, Instituto de Salud Carlos III (Author)
  • Anne-Paule Gimenez-Roqueplo - , Assistance publique – Hôpitaux de Paris (Author)
  • Ashley B Grossman - , Royal Free London NHS Foundation Trust (Author)
  • David Taïeb - , Assistance publique - Hôpitaux de Marseille (Author)
  • Eamonn R Maher - , NIHR Cambridge Biomedical Research Centre (BCR) (Author)
  • Jacques W M Lenders - , Radboud University Medical Center (Author)
  • Graeme Eisenhofer - , Department of Internal Medicine III, University Hospital Carl Gustav Carus Dresden (Author)
  • Camilo Jimenez - , University of Texas MD Anderson Cancer Center (Author)
  • Karel Pacak - , Eunice Kennedy Shriver National Institute of Child Health and Human Development (Author)
  • Christina Pamporaki - , Department of Internal Medicine III (Author)

Abstract

Phaeochromocytomas and paragangliomas (PPGL) are rare neuroendocrine tumours that arise not only in adulthood but also in childhood and adolescence. Up to 70-80% of childhood PPGL are hereditary, accounting for a higher incidence of metastatic and/or multifocal PPGL in paediatric patients than in adult patients. Key differences in the tumour biology and management, together with rare disease incidence and therapeutic challenges in paediatric compared with adult patients, mandate close expert cross-disciplinary teamwork. Teams should ideally include adult and paediatric endocrinologists, oncologists, cardiologists, surgeons, geneticists, pathologists, radiologists, clinical psychologists and nuclear medicine physicians. Provision of an international Consensus Statement should improve care and outcomes for children and adolescents with these tumours.

Details

Original languageEnglish
Pages (from-to)729-748
Number of pages20
JournalNature reviews. Endocrinology
Volume20
Issue number12
Publication statusPublished - Dec 2024
Peer-reviewedYes

External IDs

Scopus 85201542262
ORCID /0000-0002-7278-5711/work/173989216

Keywords

Keywords

  • Humans, Pheochromocytoma/therapy, Paraganglioma/therapy, Adolescent, Child, Adrenal Gland Neoplasms/therapy, Consensus