Helical motion and torque generation by microtubule motors
Research output: Contribution to journal › Review article › Contributed › peer-review
Contributors
Abstract
Microtubule motors play key roles in cellular functions, such as transport, mitosis and cell motility. Fueled by ATP hydrolysis, they convert chemical energy into mechanical work, which enables their movement on microtubules. While their motion along the long axis of microtubules has been studied extensively, some motors display an off-axis component, which results in helical motion around microtubules and the generation of torque in addition to linear forces. Understanding these nuanced movements expands our comprehension of motor protein dynamics and their impact on cellular processes.
Details
| Original language | English |
|---|---|
| Article number | 102367 |
| Number of pages | 9 |
| Journal | Current opinion in cell biology |
| Volume | 88 |
| Publication status | Published - Jun 2024 |
| Peer-reviewed | Yes |
External IDs
| PubMed | 38735207 |
|---|---|
| ORCID | /0000-0002-0750-8515/work/161407029 |
Keywords
ASJC Scopus subject areas
Keywords
- Microtubules/metabolism, Molecular Motor Proteins/metabolism, Torque, Humans, Animals