Helical motion and torque generation by microtubule motors

Publikation: Beitrag in FachzeitschriftÜbersichtsartikel (Review)BeigetragenBegutachtung

Abstract

Microtubule motors play key roles in cellular functions, such as transport, mitosis and cell motility. Fueled by ATP hydrolysis, they convert chemical energy into mechanical work, which enables their movement on microtubules. While their motion along the long axis of microtubules has been studied extensively, some motors display an off-axis component, which results in helical motion around microtubules and the generation of torque in addition to linear forces. Understanding these nuanced movements expands our comprehension of motor protein dynamics and their impact on cellular processes.

Details

OriginalspracheEnglisch
Aufsatznummer102367
FachzeitschriftCurrent opinion in cell biology
Jahrgang88
PublikationsstatusVeröffentlicht - Juni 2024
Peer-Review-StatusJa

Externe IDs

PubMed 38735207
ORCID /0000-0002-0750-8515/work/161407029

Schlagworte

ASJC Scopus Sachgebiete

Schlagwörter

  • Microtubules/metabolism, Molecular Motor Proteins/metabolism, Torque, Humans, Animals