External compression increases forearm perfusion

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

Abstract

Application of compression stockings to the lower extremities is a widely used therapeutic intervention to improve venous return, but there is little information about the effects of compression on local arterial perfusion. Therefore, we tested the hypothesis that a positive external pressure increases forearm perfusion. The relation of increasing external pressure induced by standardized compression to the arterial inflow and arterial flow reserve of the forearm was critically evaluated in a group of healthy young men (n = 9). Row was measured with venous occlusion plethysmography after a 10-min application of six different stockings with compression pressure increasing from 13 to 23 mmHg. During compression, the arterial inflow increased significantly from 3.7 ±0.85 to 8.8 ± 2.01 ml·min-1·100 ml tissue-1 (P < 0.001) and the arterial flow reserve increased from 17.7 ± 4.7 to 28.3 ± 7.0 ml·min-1·100 ml tissue-1. The flow increase was persistent after 3 h of constant application of external pressure and also during simultaneous low-intensity hand grip. Similar results obtained with occlusion plethysmography were seen with MRI. During the interventions, forearm temperature was unchanged, and the volunteers reported no discomfort. In conclusion, 1) arterial perfusion of the human forearm increases more than twofold during application of external compression over a pressure range of 13-23 mmHg, and 2) the result is interpreted as an autoregulatory response following the decrease of the vascular transmural pressure gradient.

Details

Original languageEnglish
Pages (from-to)2337-2344
Number of pages8
JournalJournal of applied physiology
Volume99
Issue number6
Publication statusPublished - Dec 2005
Peer-reviewedYes

External IDs

PubMed 16081618

Keywords

Sustainable Development Goals

ASJC Scopus subject areas

Keywords

  • Arterial inflow, Flow autoregulation, Transmural pressure, Venous occlusion plethysmography