Endoscopic optical coherence tomography device for forward imaging with broad field of view
Research output: Contribution to journal › Research article › Contributed › peer-review
Contributors
Abstract
One current challenge of studying human tympanic membranes (TM) with optical coherence tomography (OCT) is the implementation of optics that avoid direct contact with the inflamed tissue. At the moment, no commercial device is available. We report an optics design for contactless forward imaging endoscopic optical coherence tomography (EOCT) with a large working distance (WD) and a broad field of view (FOV) by restricting the overall diameter of the probe to be small (3.5 mm), ensuring a sufficient numerical aperture. Our system uses a gradient-index (GRIN) relay lens and a GRIN objective lens, and executes a fan-shaped optical scanning pattern. The WD and FOV can be adjusted by manually changing the distance between the triplet and the GRIN relay lens. The measured lateral resolution is ∼28 μm at a WD of 10 mm with a FOV of 10 mm. Additionally, a camera and an illumination beam path were implemented within the probe for image guidance during investigations of the TM. We demonstrated the performance of the EOCT design by 3-D imaging of a human TM ex vivo and in vivo with a k-linear spectral domain OCT system.
Details
Original language | English |
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Article number | 071302 |
Journal | Journal of Biomedical Optics |
Volume | 17 |
Issue number | 7 |
Publication status | Published - Jul 2012 |
Peer-reviewed | Yes |
External IDs
Scopus | 84872030095 |
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PubMed | 22894463 |
ORCID | /0000-0003-0554-2178/work/142249768 |
ORCID | /0000-0003-2292-5533/work/142256540 |
Keywords
ASJC Scopus subject areas
Keywords
- Endoscopic optical coherence tomography, Field of view, Gradient index, Tympanic membrane