Don't trick me twice!
Research output: Contribution to journal › Editorial (Lead article) › Invited › peer-review
Contributors
Abstract
Chemotherapy-induced nephrotoxicity limits the success of cancer therapy. Landau et al. now describe a mechanism by which a first dose of cisplatin renders the kidney sensitive to necroptosis mediated by a second dose. Unresolved injury and sustained necrosis, therefore, may represent a pathophysiological means of transition from acute kidney injury to chronic kidney disease.
Details
Original language | English |
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Pages (from-to) | 736-738 |
Number of pages | 3 |
Journal | Kidney international |
Volume | 95 |
Issue number | 4 |
Publication status | Published - Apr 2019 |
Peer-reviewed | Yes |
External IDs
Scopus | 85062805616 |
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ORCID | /0000-0001-6287-9725/work/145698891 |
ORCID | /0000-0002-9728-1413/work/145699157 |
Keywords
Sustainable Development Goals
Keywords
- Acute Kidney Injury, Cisplatin, Humans, Kidney, Necrosis, Renal Insufficiency, Chronic