Don't trick me twice!

Publikation: Beitrag in FachzeitschriftLeitartikel (Editorial)EingeladenBegutachtung

Beitragende

Abstract

Chemotherapy-induced nephrotoxicity limits the success of cancer therapy. Landau et al. now describe a mechanism by which a first dose of cisplatin renders the kidney sensitive to necroptosis mediated by a second dose. Unresolved injury and sustained necrosis, therefore, may represent a pathophysiological means of transition from acute kidney injury to chronic kidney disease.

Details

OriginalspracheEnglisch
Seiten (von - bis)736-738
Seitenumfang3
FachzeitschriftKidney international
Jahrgang95
Ausgabenummer4
PublikationsstatusVeröffentlicht - Apr. 2019
Peer-Review-StatusJa

Externe IDs

Scopus 85062805616
ORCID /0000-0001-6287-9725/work/145698891
ORCID /0000-0002-9728-1413/work/145699157

Schlagworte

Ziele für nachhaltige Entwicklung

Schlagwörter

  • Acute Kidney Injury, Cisplatin, Humans, Kidney, Necrosis, Renal Insufficiency, Chronic