Don't trick me twice!
Publikation: Beitrag in Fachzeitschrift › Leitartikel (Editorial) › Eingeladen › Begutachtung
Beitragende
Abstract
Chemotherapy-induced nephrotoxicity limits the success of cancer therapy. Landau et al. now describe a mechanism by which a first dose of cisplatin renders the kidney sensitive to necroptosis mediated by a second dose. Unresolved injury and sustained necrosis, therefore, may represent a pathophysiological means of transition from acute kidney injury to chronic kidney disease.
Details
Originalsprache | Englisch |
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Seiten (von - bis) | 736-738 |
Seitenumfang | 3 |
Fachzeitschrift | Kidney international |
Jahrgang | 95 |
Ausgabenummer | 4 |
Publikationsstatus | Veröffentlicht - Apr. 2019 |
Peer-Review-Status | Ja |
Externe IDs
Scopus | 85062805616 |
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ORCID | /0000-0001-6287-9725/work/145698891 |
ORCID | /0000-0002-9728-1413/work/145699157 |
Schlagworte
Ziele für nachhaltige Entwicklung
Schlagwörter
- Acute Kidney Injury, Cisplatin, Humans, Kidney, Necrosis, Renal Insufficiency, Chronic