Die neue Definition und Klassifikation der pulmonalen Hypertonie

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

  • Philipp Douschan - , Ludwig Boltzmann Institute for Lung Vascular Research, Medical University of Graz (Author)
  • Benjamin Egenlauf - , University Hospital Heidelberg (Author)
  • Henning Gall - , Institute for Lung Health (ILH) (Author)
  • Ekkehard Grünig - , University Hospital Heidelberg (Author)
  • Alfred Hager - , Technical University of Munich (Author)
  • Melanie Heberling - , Department of internal Medicine I, University Hospital Carl Gustav Carus Dresden (Author)
  • Thomas Koehler - , University Medical Center Freiburg (Author)
  • Horst Olschewski - , Ludwig Boltzmann Institute for Lung Vascular Research, Medical University of Graz (Author)
  • Hans-Jürgen Seyfarth - , University Hospital Leipzig (Author)
  • Athiththan Yogeswaran - , Institute for Lung Health (ILH) (Author)
  • Silvia Ulrich - , University Hospital Zurich (Author)
  • Gabor Kovacs - , Ludwig Boltzmann Institute for Lung Vascular Research, Medical University of Graz (Author)

Abstract

In the recent ESC/ERS guidelines on the diagnosis and management of pulmonary hypertension (PH) several important changes have been made in respect of the definition and classification of PH.The mPAP cut-off for defining PH was lowered. PH is now defined by an mPAP > 20 mmHg assessed by right heart catheterization. Moreover, the PVR threshold for defining precapillary PH was lowered. Precapillary PH is now defined by a PVR > 2 WU and a pulmonary arterial wedge pressure (PAWP) ≤ 15 mmHg. Furthermore, the increasing evidence for the clinical relevance of pulmonary exercise hemodynamics led to the reintroduction of exercise pulmonary hypertension (EPH) 1. EPH is characterized by a mPAP/CO-slope > 3 mmHg/L/min during exercise testing. In the classification of PH five groups are distinguished: Pulmonary arterial hypertension (group 1), PH associated with left heart disease (group 2), PH associated with lung diseases and/or hypoxia (Group 3), PH associated with pulmonary artery obstructions (group 4) and PH with unclear and/or multi-factorial mechanisms (group 5).In the following guideline-translation we focus on novel aspects regarding the definition and classification of PH and to provide additional background information.

Translated title of the contribution
New definition and classification of pulmonary hypertension

Details

Original languageGerman
Pages (from-to)854-861
Number of pages8
JournalPneumologie
Volume77
Issue number11
Publication statusPublished - Nov 2023
Peer-reviewedYes

External IDs

Scopus 85177103506

Keywords

Keywords

  • Humans, Hypertension, Pulmonary/diagnosis, Hemodynamics, Heart Diseases, Cardiac Catheterization, Pulmonary Artery