Die neue Definition und Klassifikation der pulmonalen Hypertonie
Publikation: Beitrag in Fachzeitschrift › Forschungsartikel › Beigetragen › Begutachtung
Beitragende
Abstract
In the recent ESC/ERS guidelines on the diagnosis and management of pulmonary hypertension (PH) several important changes have been made in respect of the definition and classification of PH.The mPAP cut-off for defining PH was lowered. PH is now defined by an mPAP > 20 mmHg assessed by right heart catheterization. Moreover, the PVR threshold for defining precapillary PH was lowered. Precapillary PH is now defined by a PVR > 2 WU and a pulmonary arterial wedge pressure (PAWP) ≤ 15 mmHg. Furthermore, the increasing evidence for the clinical relevance of pulmonary exercise hemodynamics led to the reintroduction of exercise pulmonary hypertension (EPH) 1. EPH is characterized by a mPAP/CO-slope > 3 mmHg/L/min during exercise testing. In the classification of PH five groups are distinguished: Pulmonary arterial hypertension (group 1), PH associated with left heart disease (group 2), PH associated with lung diseases and/or hypoxia (Group 3), PH associated with pulmonary artery obstructions (group 4) and PH with unclear and/or multi-factorial mechanisms (group 5).In the following guideline-translation we focus on novel aspects regarding the definition and classification of PH and to provide additional background information.
Details
Originalsprache | Deutsch |
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Seiten (von - bis) | 854-861 |
Seitenumfang | 8 |
Fachzeitschrift | Pneumologie |
Jahrgang | 77 |
Ausgabenummer | 11 |
Publikationsstatus | Veröffentlicht - Nov. 2023 |
Peer-Review-Status | Ja |
Externe IDs
Scopus | 85177103506 |
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Schlagworte
Schlagwörter
- Humans, Hypertension, Pulmonary/diagnosis, Hemodynamics, Heart Diseases, Cardiac Catheterization, Pulmonary Artery