Die neue Definition und Klassifikation der pulmonalen Hypertonie

Publikation: Beitrag in FachzeitschriftForschungsartikelBeigetragenBegutachtung

Beitragende

  • Philipp Douschan - , Ludwig Boltzmann Institute for Lung Vascular Research, Medizinische Universität Graz (Autor:in)
  • Benjamin Egenlauf - , Universitätsklinikum Heidelberg (Autor:in)
  • Henning Gall - , Institute for Lung Health (ILH) (Autor:in)
  • Ekkehard Grünig - , Universitätsklinikum Heidelberg (Autor:in)
  • Alfred Hager - , Technische Universität München (Autor:in)
  • Melanie Heberling - , Medizinische Klinik und Poliklinik I, Universitätsklinikum Carl Gustav Carus Dresden (Autor:in)
  • Thomas Koehler - , Universitätsklinikum Freiburg (Autor:in)
  • Horst Olschewski - , Ludwig Boltzmann Institute for Lung Vascular Research, Medizinische Universität Graz (Autor:in)
  • Hans-Jürgen Seyfarth - , Universitätsklinikum Leipzig (Autor:in)
  • Athiththan Yogeswaran - , Institute for Lung Health (ILH) (Autor:in)
  • Silvia Ulrich - , Universitätsspital Zürich (Autor:in)
  • Gabor Kovacs - , Ludwig Boltzmann Institute for Lung Vascular Research, Medizinische Universität Graz (Autor:in)

Abstract

In the recent ESC/ERS guidelines on the diagnosis and management of pulmonary hypertension (PH) several important changes have been made in respect of the definition and classification of PH.The mPAP cut-off for defining PH was lowered. PH is now defined by an mPAP > 20 mmHg assessed by right heart catheterization. Moreover, the PVR threshold for defining precapillary PH was lowered. Precapillary PH is now defined by a PVR > 2 WU and a pulmonary arterial wedge pressure (PAWP) ≤ 15 mmHg. Furthermore, the increasing evidence for the clinical relevance of pulmonary exercise hemodynamics led to the reintroduction of exercise pulmonary hypertension (EPH) 1. EPH is characterized by a mPAP/CO-slope > 3 mmHg/L/min during exercise testing. In the classification of PH five groups are distinguished: Pulmonary arterial hypertension (group 1), PH associated with left heart disease (group 2), PH associated with lung diseases and/or hypoxia (Group 3), PH associated with pulmonary artery obstructions (group 4) and PH with unclear and/or multi-factorial mechanisms (group 5).In the following guideline-translation we focus on novel aspects regarding the definition and classification of PH and to provide additional background information.

Details

OriginalspracheDeutsch
Seiten (von - bis)854-861
Seitenumfang8
FachzeitschriftPneumologie
Jahrgang77
Ausgabenummer11
PublikationsstatusVeröffentlicht - Nov. 2023
Peer-Review-StatusJa

Externe IDs

Scopus 85177103506

Schlagworte

Schlagwörter

  • Humans, Hypertension, Pulmonary/diagnosis, Hemodynamics, Heart Diseases, Cardiac Catheterization, Pulmonary Artery