Chromatin remodelers: a concise introduction for biophysicists

Research output: Contribution to journalReview articleContributedpeer-review

Contributors

Abstract

Chromatin remodelers are molecular motors that act on nucleosomes: they move them along DNA or (dis-)assemble them. Despite the fact that they perform essential regulatory functions in cells—their deregulation can contribute to the development of cancers and lead to cell death—chromatin remodelers have only received meager attention in the biophysics community so far. In this short text, we attempt to present the key features of this interesting class of enzymes obtained with different experimental and theoretical methods, thereby providing a concise introduction for biophysicists to further stimulate interest in their properties.

Details

Original languageEnglish
Pages (from-to)357-363
Number of pages7
JournalBiophysical reviews
Volume16
Issue number3
Publication statusPublished - Jun 2024
Peer-reviewedYes

External IDs

Mendeley 2e6a0275-7678-38ff-885a-f053f6dc3291
ORCID /0000-0003-0485-5260/work/162348554
PubMed 39099840

Keywords

Sustainable Development Goals

Keywords

  • Chromatin remodelers, Enzyme, Molecular motor, Nucleosomes