Chromatin remodelers: a concise introduction for biophysicists

Publikation: Beitrag in FachzeitschriftÜbersichtsartikel (Review)BeigetragenBegutachtung

Beitragende

Abstract

Chromatin remodelers are molecular motors that act on nucleosomes: they move them along DNA or (dis-)assemble them. Despite the fact that they perform essential regulatory functions in cells—their deregulation can contribute to the development of cancers and lead to cell death—chromatin remodelers have only received meager attention in the biophysics community so far. In this short text, we attempt to present the key features of this interesting class of enzymes obtained with different experimental and theoretical methods, thereby providing a concise introduction for biophysicists to further stimulate interest in their properties.

Details

OriginalspracheEnglisch
Seiten (von - bis)357-363
Seitenumfang7
FachzeitschriftBiophysical reviews
Jahrgang16
Ausgabenummer3
PublikationsstatusVeröffentlicht - Juni 2024
Peer-Review-StatusJa

Externe IDs

Mendeley 2e6a0275-7678-38ff-885a-f053f6dc3291
ORCID /0000-0003-0485-5260/work/162348554
PubMed 39099840

Schlagworte

Ziele für nachhaltige Entwicklung

Schlagwörter

  • Chromatin remodelers, Enzyme, Molecular motor, Nucleosomes