Calibration-free quantitative phase imaging in multi-core fiber endoscopes using end-to-end deep learning

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

  • Jiawei Sun - , Chair of Measurement and Sensor System Technique, Shanghai Artificial Intelligence Laboratory (Author)
  • Bin Zhao - , Shanghai Artificial Intelligence Laboratory, Northwestern Polytechnical University Xian (Author)
  • Dong Wang - , Shanghai Artificial Intelligence Laboratory (Author)
  • Zhigang Wang - , Shanghai Artificial Intelligence Laboratory (Author)
  • Jie Zhang - , Shanghai Artificial Intelligence Laboratory, TUD Dresden University of Technology (Author)
  • Nektarios Koukourakis - , Chair of Measurement and Sensor System Technique, TUD Dresden University of Technology (Author)
  • Júergen W. Czarske - , Chair of Measurement and Sensor System Technique, TUD Dresden University of Technology (Author)
  • Xuelong Li - , Shanghai Artificial Intelligence Laboratory, Northwestern Polytechnical University Xian (Author)

Abstract

Quantitative phase imaging (QPI) through multi-core fibers (MCFs) has been an emerging in vivo label-free endoscopic imaging modality with minimal invasiveness. However, the computational demands of conventional iterative phase retrieval algorithms have limited their real-time imaging potential. We demonstrate a learning-based MCF phase imaging method that significantly reduced the phase reconstruction time to 5.5 ms, enabling video-rate imaging at 181 fps. Moreover, we introduce an innovative optical system that automatically generated the first, to the best of our knowledge, open-source dataset tailored for MCF phase imaging, comprising 50,176 paired speckles and phase images. Our trained deep neural network (DNN) demonstrates a robust phase reconstruction performance in experiments with a mean fidelity of up to 99.8%. Such an efficient fiber phase imaging approach can broaden the applications of QPI in hard-to-reach areas.

Details

Original languageEnglish
Pages (from-to)342-345
Number of pages4
JournalOptics letters
Volume49
Issue number2
Publication statusPublished - 15 Jan 2024
Peer-reviewedYes

External IDs

PubMed 38194563

Keywords