Buckling Instability of Viral Capsids—A Continuum Approach
Research output: Contribution to journal › Research article › Contributed › peer-review
Contributors
Abstract
The crystallographic structure of spherical viruses is modeled using a multiscale approach combining a macroscopic Helfrich model for morphology evolution with a microscopic approximation of a classical density functional theory for the protein interactions. The derivation of the model is based on energy dissipation and conservation of protein number density. The resulting set of equations is solved within a diffuse domain approach using finite elements and shows buckling transitions of spherical shapes into faceted viral shapes.
Details
Original language | English |
---|---|
Pages (from-to) | 82-110 |
Journal | Multiscale modeling & simulation |
Volume | 10 |
Issue number | 1 |
Publication status | Published - 2012 |
Peer-reviewed | Yes |
External IDs
WOS | 000302183800005 |
---|---|
Scopus | 84861492057 |