Buckling Instability of Viral Capsids—A Continuum Approach

Publikation: Beitrag in FachzeitschriftForschungsartikelBeigetragenBegutachtung

Beitragende

Abstract

The crystallographic structure of spherical viruses is modeled using a multiscale approach combining a macroscopic Helfrich model for morphology evolution with a microscopic approximation of a classical density functional theory for the protein interactions. The derivation of the model is based on energy dissipation and conservation of protein number density. The resulting set of equations is solved within a diffuse domain approach using finite elements and shows buckling transitions of spherical shapes into faceted viral shapes.

Details

OriginalspracheEnglisch
Seiten (von - bis)82-110
FachzeitschriftMultiscale modeling & simulation
Jahrgang10
Ausgabenummer1
PublikationsstatusVeröffentlicht - 2012
Peer-Review-StatusJa

Externe IDs

WOS 000302183800005
Scopus 84861492057

Schlagworte

Bibliotheksschlagworte