Buckling Instability of Viral Capsids—A Continuum Approach
Publikation: Beitrag in Fachzeitschrift › Forschungsartikel › Beigetragen › Begutachtung
Beitragende
Abstract
The crystallographic structure of spherical viruses is modeled using a multiscale approach combining a macroscopic Helfrich model for morphology evolution with a microscopic approximation of a classical density functional theory for the protein interactions. The derivation of the model is based on energy dissipation and conservation of protein number density. The resulting set of equations is solved within a diffuse domain approach using finite elements and shows buckling transitions of spherical shapes into faceted viral shapes.
Details
Originalsprache | Englisch |
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Seiten (von - bis) | 82-110 |
Fachzeitschrift | Multiscale modeling & simulation |
Jahrgang | 10 |
Ausgabenummer | 1 |
Publikationsstatus | Veröffentlicht - 2012 |
Peer-Review-Status | Ja |
Externe IDs
WOS | 000302183800005 |
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Scopus | 84861492057 |