AGEs in foods: Do they play a role in uremia?

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

  • TUD Dresden University of Technology

Abstract

The so-called Maillard reaction, or nonenzymatic glycation between proteins and carbohydrates, is of particular importance for the flavor, color, and shelf life of food. Despite the great variety of possible AGEs, which can be formed during heating processes, only a few have unequivocally been identified and quantified in foods. From the quantitative point of view, the amount of AGEs ingested with a conventional diet is much higher than the total amount of AGEs in the plasma and tissue. To date, however, only preliminary studies concerning digestion, resorption, and elimination of AGE-modified food proteins can be found in the literature, indicating that for patients with impaired kidney function, dietary AGEs might contribute significantly to the total AGE load of the body. To date, however, no conclusive answers or recommendations can be given regarding a possible role of AGEs as uremic toxins in general, and of dietary AGEs in particular.

Details

Original languageEnglish
Pages (from-to)S145-S147
Number of pages3
JournalKidney international
Volume63
Publication statusPublished - May 2003
Peer-reviewedYes

Conference

TitleInternational Congress on Uremic Toxicity
Duration13 - 16 September 2002
CityWURZBURG
CountryGermany

External IDs

Scopus 0037406409

Keywords

Sustainable Development Goals

Keywords

  • N-EPSILON-CARBOXYMETHYLLYSINE, GLYCATION END-PRODUCTS, MILK-PRODUCTS, DIABETIC NEPHROPATHY, MAILLARD-REACTION, IDENTIFICATION, METHYLGLYOXAL, PROTEIN, EXTENT