Polyacrylamide gels containing ionized functional groups for the molecular imprinting of human growth hormone
Publikation: Beitrag in Fachzeitschrift › Forschungsartikel › Beigetragen › Begutachtung
Beitragende
Abstract
Networks of polyacrylamide having methacrylic acid and 2-(dimethylamino)ethyl methacrylate incorporated were studied for the possibility of imprinting human growth hormone. Two templates - the monomeric and the dimeric molecular forms of human growth hormone hormone - were for the first time imprinted using a hydrogel containing charged functional groups. The results show that approximately 90% (w/w) of the templates could be extracted from the molecularly imprinted acrylamide polymers. The molecularly imprinted polymer adsorbed approximately 70 times (for the monomeric form of the hormone) and 60 times (for the dimeric form) more of the template than of the non-imprinted polymer. The selectivity of the molecularly imprinted polymers was also studied.
Details
Originalsprache | Englisch |
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Seiten (von - bis) | 611-617 |
Seitenumfang | 7 |
Fachzeitschrift | Polymer bulletin |
Jahrgang | 58 |
Ausgabenummer | 3 |
Publikationsstatus | Veröffentlicht - März 2007 |
Peer-Review-Status | Ja |
Extern publiziert | Ja |
Externe IDs
Scopus | 33846609612 |
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ORCID | /0000-0002-4531-691X/work/148607744 |
ORCID | /0000-0003-0189-3448/work/159607205 |
Schlagworte
Schlagwörter
- Polymer particles, Recognition, Peptides, Lysozyme, Sites