This research aims to produce an E-learning instructional model for vocational schools (VS) in Indonesia by implementing a system of E-learning instructional design that allows teachers to develop and teach their own e-learning lebons. This study reports a design-based research and development activity which was performed over three years, 2012-2014. In the first year, abebment and development of criteria for E-learning & instructional design in VS and its indicators were performed. The second year was used to develop a guide book of E-learning instructional design in VSs, based on the results of the first year of the study when a focus group discubion (FGD) was held to discub, test, and revise the draft guidebook. In the third year the dibemination of E-learning instructional design was executed, involving 22 teachers from around Yogyakarta Province. Quantitative analysis of the E-learning instructional model in VS led to different values of adoption for the specific components, such as guidebooks, learning modules, and DVD based training. The final results showed that the model of E-learning instruction in VS is suitable to support and motivate the teachers in dibemination and for developing their teaching material by using the E-learning instructional model guidebook.