The hot deformation behavior of a Ti-5Al-5Mo-5V-3Cr alloy obtained by the Blended Elemental Powder Metallurgy approach was investigated. The hot compression tests were carried out to determine the stress-strain relationships at the temperature range of 
800 °C to 1000 °C and strain rate between 0.1 s^-1 and 20 s^-1. The constitutive model based on the Arrhenius-type constitutive equation was developed as well as the deformation activation energy map. Based on the Dynamic Material Model theory, processing maps at constant strain values were developed using data obtained from hot compression tests. The processing window that indicated the optimum hot deformation parameters was determined at the temperature range of 900 ºC to 1000 ºC and strain rates of 0.1 – 2.0 s^-1. The verification of the developed results was successfully confirmed based on the observations of the microstructures of samples after hot compression tests. Then, the hot rolling process was designed using FEM modeling and successfully verified by laboratory tests. The relationship of the deformation parameters, microstructure, and hardness of Ti-5Al-5Mo-5V-3Cr alloy was analyzed.