Abdominal wall hernia repair mostly involves the implantation of a synthetic mesh material. The link between the mesh microstructure, mechanical behaviour and clinical outcome is still not fully understood, complicating the selection of a suitable patient-specific mesh. Here, we created a parametric 3D model of a synthetic mesh based on X-ray microfocus computed tomography (XCT) images. The model was implemented in a TexMind Warp Knitting Editor software and then exported for finite element model (FEM) analysis. This model allows better understanding of the mechanical behaviour of the mesh and identifying the influence of single structural parameters that are essential for the design of the mesh. We also used the XCT-based filament paths to directly build a FEM, representing all 3D structural details of the as-produced product. Whilst the mechanical analysis of the mesh is feasible, important difficulties are identified, related to the initial relaxed mesh contacts configuration and necessity of the mesh pretension in experiments and calculations.