Waddington's valleys and Captain Cook's islands

Research output: Contribution to journalResearch articleInvited

Contributors

  • Michael H Sieweke - , Marseille-Luminy Immunology Center (CIML), INSERM - Institut national de la santé et de la recherche médicale, French National Centre for Scientific Research (CNRS), Max Delbrück Center for Molecular Medicine (MDC) (Author)

Abstract

Somatic reprogramming has relied heavily on theoretical models that view differentiation in terms of developmental branch point decisions. Recent studies in Cell now reveal a dominant role of the microenvironment in shaping epigenetic identity of macrophages, thus providing support for alternative models of cell fate acquisition.

Details

Original languageEnglish
Pages (from-to)7-8
Number of pages2
JournalCell Stem Cell
Volume16
Issue number1
Publication statusPublished - 8 Jan 2015
Peer-reviewedNo
Externally publishedYes

External IDs

Scopus 84920749813

Keywords