Visceral fat mass dynamics in a 2-year randomized STrength versus ENdurance training trial in people with obesity

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

  • Stefanie Lehmann - , Leipzig University (Author)
  • Ulf Retschlag - , Leipzig University (Author)
  • Andreas Oberbach - , Hospital of the Ludwig-Maximilians-University (LMU) Munich (Author)
  • Roland Morgenroth - , University Hospital Leipzig (Author)
  • Nicolas Linder - , University Hospital Leipzig (Author)
  • Alexander Schaudinn - , University Hospital Leipzig (Author)
  • Nikita Garnov - , University Hospital Leipzig (Author)
  • Harald Busse - , University Hospital Leipzig (Author)
  • Kilian Solty - , University Hospital Leipzig (Author)
  • Christiane Prettin - , Leipzig University (Author)
  • Nicole Köppe-Bauernfeind - , Leipzig University (Author)
  • Gesine Flehmig - , University Hospital Leipzig (Author)
  • Lars Selig - , Leipzig University (Author)
  • Evelyn Trips - , Leipzig University (Author)
  • Michael Stumvoll - , Helmholtz Institute for Metabolic, Obesity and Vascular Research (Author)
  • David Petroff - , Leipzig University (Author)
  • Matthias Blüher - , Helmholtz Institute for Metabolic, Obesity and Vascular Research (Author)

Abstract

AIM: To compare the effectiveness of strength versus endurance training on reducing visceral fat in individuals with obesity.

MATERIALS AND METHODS: For the STrength versus ENdurance (STEN) 24-month randomized clinical trial, we assigned 239 participants with abdominal obesity to either strength or endurance training (two to three times a week, 60 min/training session) in addition to standard nutritional counselling to promote a healthy diet. Changes in abdominal visceral adipose tissue (VAT) area quantified by magnetic resonance imaging after 12 months were defined as a primary endpoint.

RESULTS: Participants (aged 44 years, 74% women, body mass index: 37 kg/m2, mean VAT volume: 4050 cm3) had an approximately 50% retention rate and a 30% good training programme adherence at 12 months. There was no difference between strength and endurance training in VAT volume dynamics after 12 and 24 months (p = .13). Only in the good adherence group did we find a trend for reduced VAT volume in both training regimens. Independently of the exercise programme, there was a continuous trend for moderate loss of abdominal subcutaneous AT volume, body fat mass, body mass index and improved parameters of insulin sensitivity. Although parameters of physical fitness improved upon both exercise interventions, the dynamics of resting energy expenditure, glucose and lipid metabolism parameters were not different between the intervention groups and did not significantly improve during the 2-year trial (p > .05).

CONCLUSIONS: Despite heterogeneous individual training responses, strength and endurance training neither affected VAT volume nor key secondary endpoints differently.

Details

Original languageEnglish
Pages (from-to)4087-4099
Number of pages13
JournalDiabetes, Obesity and Metabolism
Volume26
Issue number9
Publication statusPublished - Sept 2024
Peer-reviewedYes
Externally publishedYes

External IDs

Scopus 85198753006
ORCID /0000-0002-6530-5855/work/166765341

Keywords

Sustainable Development Goals

Keywords

  • Adult, Body Mass Index, Endurance Training/methods, Energy Metabolism/physiology, Female, Humans, Insulin Resistance/physiology, Intra-Abdominal Fat/diagnostic imaging, Magnetic Resonance Imaging, Male, Middle Aged, Obesity, Abdominal/therapy, Resistance Training/methods, Treatment Outcome, Weight Loss/physiology