Video-rate lensless endoscope with self-calibration using wavefront shaping

Research output: Contribution to journalResearch articleContributedpeer-review

Abstract

Lensless fiber endoscopes are of great importance for keyhole imaging. Coherent fiber bundles (CFB) can be used in endoscopes as remote phased arrays to capture images. One challenge is to image at high speed while correcting aberrations induced by the CFB. We propose the combination of digital optical phase conjugation, using a spatial light modulator, with fast scanning, for which a 2D galvo scanner and an adaptive lens are employed. We achieve the transmission of laser and image scanning through the CFB. Video-rate imaging at 20 Hz in 2D with subcellular resolution is demonstrated in 3D with 1 Hz. The sub-millimeter-diameter scanning endoscope has a great potential in biomedicine, for manipulation, e.g., in optogenetics, as well as in imaging.

Details

Original languageEnglish
Pages (from-to)3629-3632
Number of pages4
JournalOptics letters
Volume45
Issue number13
Publication statusPublished - 1 Jul 2020
Peer-reviewedYes

External IDs

PubMed 32630916
ORCID /0000-0002-8321-7488/work/190133919

Keywords