UNICORE – a Middleware for Life Sciences Grids

Research output: Contribution to book/conference proceedings/anthology/reportChapter in book/anthology/reportContributed


  • Piotr Bala - , University of Warsaw (Author)
  • Kim Baldridge - , University of Zurich (Author)
  • Emilio Benfenati - , IRCCS Istituto di ricerche farmacologiche Mario Negri - Milano, Bergamo, Ranica (Author)
  • Mose Casalegno - , IRCCS Istituto di ricerche farmacologiche Mario Negri - Milano, Bergamo, Ranica (Author)
  • Uko Maran - , University of Tartu (Author)
  • Lukasz Miroslaw - , University of Zurich (Author)
  • Vitaliy Ostropytskyy - , Ulster University (Author)
  • Katharina Rasch - (Author)
  • Sulev Sild - , University of Tartu (Author)
  • Robert Schöne - , Center for Information Services and High Performance Computing (ZIH) (Author)
  • Nigel Williams - (Author)


This chapter provides an overview of Grid middleware and applications related to biomedical and life sciences disciplines. Various technologies, including web-based solutions, are presented. One of the solutions, the UNICORE framework, in its recent version implements key grid standards and specifications. The system architecture and capabilities, such as security, workflow and data management are described. Special attention is given to the idea of a ‘gridbean’, which expands the UNICORE use for different applications. Examples of gridbeans are provided and the capabilities of UNICORE are illustrated through specific examples built using this grid middleware. In particular, the Chemomentum workbench and its use for in-silico design and modeling in chemistry and life sciences are both described.


Original languageEnglish
Title of host publicationHandbook of Research on Computational GRID Technologies for Life Sciences, Biomedicine, and Healthcare
PublisherIGI Global
Publication statusPublished - 2008

External IDs

ORCID /0009-0003-0666-4166/work/151475556