Überprüfung von Nachtrunkbehauptungen mittels getränke- charakteristischer Aromastoffe in Blut-/Serumproben
Research output: Contribution to journal › Research article › Contributed › peer-review
Contributors
Abstract
For the first time, the results of the present investigation allow a survey of post-offence alcohol drinking claims by means of characteristic flavourings in blood/scrum samples. For that purpose, the beverage flavouring agents including anethole, eugenol, carvone, menthone, isomenthone, neomenthol and menthol were selected from spirits. These substances are mainly found in spirits being poor in congeners, in which the validation of a post offence drinking claim is impeded by conventional congener analysis. The investigation of flavouring agents provides a considerable improvement in the validation of post offence drinking claims. To detect these flavourings in the serum a sensitive analytical method was developed. From the results of experiments, the metabolism and pharmacokinetics of these compounds were examined. Formulas being similar to the "Bonteformulas" were created to determine the calculation values of the kinetics. Finally, an error estimate has been carried out. The analysis method was proved to be practicable because these flavourings actually were detected in numerous blood/serum samples after consumption of appropriate spirits. In cases where no relevant flavouring spirits were consumed, no flavourings could be detected.
Translated title of the contribution | Validation of post-offence alcohol drinking claims on the basis of beverage-characteristic flavourings in blood-/serum samples |
---|
Details
Original language | German |
---|---|
Pages (from-to) | 231-238 |
Number of pages | 8 |
Journal | Blutalkohol |
Volume | 54 |
Issue number | 4 |
Publication status | Published - Jul 2017 |
Peer-reviewed | Yes |
Keywords
ASJC Scopus subject areas
Keywords
- Congener analysis, Flavourings, HS-SPME-GC-MS, Post-offence alcohol drinking claims