Objective: The consensus recommendations for the assessment of occupational disease no. 2108 as well as occupational disease no. 2110 (disc-related diseases of the lumbar spine) require that at least one of three additional criteria is fulfilled in the most frequent case constellation (B2 constellation). Of these additional criteria two are empirically investigated in an additional analysis of the German Spine Study (EPILIFT). Methods: The two exposure-related additional criteria “particularly intensive load” (second additional criterion) and “peak loads” (third additional criterion) were investigated. We applied logistic regression analysis to calculate adjusted odds ratios for age and region (as relative risk estimates) with 95% confidence intervals (95% CI). Odds ratios were determined in the same regression models for the fulfilment and for the lack of fulfilment of an additional criterion. In principle, a criterion is suitable for distinguishing between occupationally caused and non-occupationally caused intervertebral disc-related diseases if the risk estimates are considerably higher when the respective criterion is fulfilled than when the criterion is not fulfilled. For peak loads, the level of compressive forces due to lifting and/or carrying above which the criterion of a peak load was considered to be met was varied. Furthermore, the number of shifts at which the criterion of a peak load had to be met was varied. We performed all calculations separately for men and women for the two cumulative exposure models original MDD and BSG model. Results: In the presence of a “particularly intensive load”, no higher disc-related disease risks were found than in the absence of this additional criterion. As a “best estimate”, the additional criterion “peak load” can be assumed to be fulfilled for the BSG exposure model if daily dosages of at least 2.0 kNh (kilonewton-hours = 1000 Newton-hours) per shift for men or at least 0.5 kNh for women are reached by peak loads (lumbar spine force ≥ 6.0 kN among men, ≥ 4.5 kN among women) in at least 600 shifts of the entire working life. Conclusion: The additional evaluation of the German Spine Study cannot confirm the second additional criterion of the B2 constellation “particularly intensive load”. The third additional criterion “peak loads”, on the other hand, is confirmed in principle. It should be fulfilled over at least 600 working shifts to serve as a positive criterion for the recognition of a disc-related occupational disease.