Two types of astrocytic cell in the adult striatum

Research output: Contribution to book/Conference proceedings/Anthology/ReportConference contributionContributedpeer-review

Contributors

  • Li Ping Wang - , Max Delbrück Center for Molecular Medicine (MDC), Shenzhen Institute of Advanced Technology (SIAT), CAS - Chinese Academy of Sciences (Author)
  • Giselle Cheung - , Max Delbrück Center for Molecular Medicine (MDC) (Author)
  • Golo Kronenberg - , Charité – Universitätsmedizin Berlin, Max Delbrück Center for Molecular Medicine (MDC) (Author)
  • Karen Gertz - , Charité – Universitätsmedizin Berlin (Author)
  • Shengbo Ji - , Charité – Universitätsmedizin Berlin (Author)
  • Gerd Kempermann - , Chair of Genomics of Regeneration, Max Delbrück Center for Molecular Medicine (MDC) (Author)
  • Matthias Endres - , Charité – Universitätsmedizin Berlin (Author)
  • Helmut Kettenmann - , Max Delbrück Center for Molecular Medicine (MDC) (Author)

Abstract

We studied the properties of GFAP-expressing cells in adult mouse striatum using acute brain slices from transgenic animals expressing EGFP under GFAP promoter. Under physiological conditions, two distinct populations of GFAPEGFP cells could be identified: (1) brightly fluorescent cells had bushy processes, passive membrane properties, glutamate transporter activity, and high gap junction coupling rate typical for classical astrocytes; (2) weakly fluorescent cells were characterized by thin, clearly distinguishable processes, voltage-gated currents, and low coupling rate reminiscent of an astrocyte subtype recently described in the hippocampus.

Details

Original languageEnglish
Title of host publication2008 International Conference on Information Technology and Applications in Biomedicine
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages520-524
Number of pages5
ISBN (electronic)978-1-4244-2255-5
ISBN (print)978-1-4244-2254-8
Publication statusPublished - 2008
Peer-reviewedYes

Publication series

SeriesIEEE EMBS International Conference on Information Technology Applications in Biomedicine (ITAB)

Conference

Title5th International Conference on Information Technology and Applications in Biomedicine, ITAB 2008 in conjunction with 2nd International Symposium and Summer School on Biomedical and Health Engineering, IS3BHE 2008
Duration30 - 31 May 2008
CityShenzhen
CountryChina

External IDs

ORCID /0000-0002-5304-4061/work/142238835