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Transient Depletion of Foxp3(+) Regulatory T Cells Selectively Promotes Aggressive beta Cell Autoimmunity in Genetically Susceptible DEREG Mice

Research output: Contribution to journal › Research article › Contributed › peer-review

Contributors

Deepika Watts - , Institute of Clinical Chemistry and Laboratory Medicine (Author)
Marthe Janssen - , Chair of Molecular and Cellular Immunology - focus Immunoregulation (Author)
Mangesh Jaykar - , Institute for Immunology (Author)
Francesco Palmucci - , Center for Regenerative Therapies Dresden, Chair of Molecular and Cellular Immunology - focus Immunoregulation (Author)
Marc Weigelt - (Author)
Cathleen Petzold - , Chair of Molecular and Cellular Immunology - focus Immunoregulation (Author)
Angela Hommel - , Chair of Preclinical stem cell therapy and diabetes (Author)
Tim Sparwasser - (Author)
Ezio Bonifacio - , Chair of Preclinical stem cell therapy and diabetes, Center for Regenerative Therapies Dresden (Author)
Karsten Kretschmer - , Chair of Molecular and Cellular Immunology - focus Immunoregulation, Center for Regenerative Therapies Dresden (Author)

Details

Original language	English
Article number	720133
Journal	Frontiers in immunology
Volume	12
Publication status	Published - 10 Aug 2021
Peer-reviewed	Yes

External IDs

Scopus	85113354408
ORCID	/0000-0002-8704-4713/work/141544139
ORCID	/0000-0001-6770-4078/work/142242290

Keywords

Research priority areas of TU Dresden

Health Sciences, Biomedicine and Bioengineering

DFG Classification of Subject Areas according to Review Boards

Immunology

Sustainable Development Goals

SDG 3 - Good Health and Well-being

ASJC Scopus subject areas

Keywords

type 1 diabetes, immune regulation, Treg cells, Foxp3, cell ablation

Library keywords

610 Medicine and health