The upcoming 6G communication standard promises unrivaled bandwidth, connectivity, and coverage and will likely span from most remote places over densely populated areas into low earth orbit. The implementation of this vision, however, poses many considerable challenges to the underlying processing hardware with advanced solutions needed to meet these requirements - especially in space. These challenges include the need for significant technological advances, critical demands in terms of performance, reliability, and adaptability, and considerations in terms of the trustworthiness of devices, to name only a few of them. This paper presents our joint efforts to address these needs and enable open-source, adaptive, and fault-tolerant processing systems for 6G communication systems in low-earth orbit.