The friction potential of the suspension is typically considered to be invariant as the vertical dynamics of a vehicle are analysed. However, the current research on MacPherson suspensions indicates a strong dependence of the suspension friction on the present driving situation, which is primarily characterised by the wheel deflection relative to the chassis, and the tyre forces. Although it is well known that the shock absorber is generally subjected to side loads that can vary and initiate a certain amount of friction, the precise contribution of the shock absorber friction to the total suspension friction has yet to be investigated in detail. It is therefore essential to conduct a quantitative study on the importance of the shock absorber in the context of specific driving situations regarding the development of new, friction optimised shock absorber generations. The present study investigates the relationship between total suspension friction and the friction of the shock absorber, with a particular focus on the case of wheel lateral forces that aim to represent a simplified cornering manoeuvre of the vehicle. This is realised by using a multi-body simulation approach and a strain gauge application in order to estimate the side force at the shock absorber’s top mount. Subsequently, the shock absorber friction is determined using a test setup that considers the realistic load and mounting situation from the perspective of the MacPherson suspension subsystem. The combination of simulation and shock absorber friction measurement is sufficient to fully explain the characteristic friction trend on suspension (subsystem) level. The contribution of the shock absorber friction to the total suspension friction is determined to be a maximum of 80%, emphasising the importance of considering the side force at the shock absorber while aiming for suspension friction minimisation and ride comfort performance enhancement. On the other hand, the shock absorber’s contribution is also observed to be limited depending on the actual wheel force, indicating that the friction of the other components remains a crucial factor in the MacPherson suspension concept.