The normalized limit of detection in NMR spectroscopy

Research output: Contribution to journal › Research article › Contributed › peer-review

Contributors

  • Piotr Lepucki - , Leibniz Institute for Solid State and Materials Research Dresden (Author)
  • Adam P. Dioguardi - , Leibniz Institute for Solid State and Materials Research Dresden (Author)
  • Daniil Karnaushenko - , Leibniz Institute for Solid State and Materials Research Dresden (Author)
  • Oliver G. Schmidt - , Leibniz Institute for Solid State and Materials Research Dresden, TUD Dresden University of Technology, Chemnitz University of Technology (Author)
  • Hans Joachim Grafe - , Leibniz Institute for Solid State and Materials Research Dresden (Author)

Abstract

We derive the normalized limit of detection for frequency space (nLODf) as a parameter to measure the sensitivity of an NMR spectroscopy setup. nLODf is independent of measurement settings such as bandwidth or number of measurement points, and allows to compare performances of different setups. We demonstrate the usefulness of the new nLODf by comparing the sensitivity of NMR setups from various publications, which all use microcoils. Finally, we want to propose a standard measurement and report format for the sensitivity of new NMR setups.

Details

Original languageEnglish
Article number107077
JournalJournal of magnetic resonance
Volume332
Publication statusPublished - Nov 2021
Peer-reviewedYes

External IDs

PubMed 34634649

Keywords

ASJC Scopus subject areas

Keywords

  • Limit of detection, Microcoil, Nuclear magnetic resonance, Signal-to-noise ratio SNR, Spectroscopy