The MAIIA EPO Purification Gel Kit, 7D3—An Alternative Purification Kit for Screening and Confirmation Procedures

Research output: Contribution to journal › Research article › Contributed › peer-review

Contributors

  • Dirk Schwenke - , Institute of Doping Analysis and Sports Biochemistry Dresden (First author)
  • Julia Hempel - , Institute of Doping Analysis and Sports Biochemistry Dresden (Author)
  • Annekathrin M. Keiler - , Environmental Monitoring and Endocrinology (Research Group), Institute of Doping Analysis and Sports Biochemistry Dresden (Author)
  • Sven Voss - , Institute of Doping Analysis and Sports Biochemistry Dresden (Last author)

Abstract

In this study, the performance of the new MAIIA EPO purification kit 7D3 was evaluated for human urine samples to confirm compliance with the WADA criteria of the WADA technical document 2024 (TD2024EPO). The kit was validated for selectivity, reliability at minimum required performance levels (MRPLs), limit of detection (LOD), carryover and recovery. A total of 81 urine samples were tested for selectivity, 29 samples for reliability at MRPL, LOD and 16 samples for recovery. The kit fulfils the criteria and the requirements of the upcoming WADA TD2024EPO and presents a valid solution for the purification of ERAs from human urine for doping analyses.

Details

Original languageEnglish
JournalDrug Testing and Analysis
Publication statusE-pub ahead of print - 7 Nov 2024
Peer-reviewedYes

External IDs

ORCID /0000-0002-2157-4711/work/171551535
Scopus 85208261464

Keywords