The International Radiomics Platform - An Initiative of the German and Austrian Radiological Societies - First Application Examples

Research output: Contribution to journalResearch articleContributedpeer-review

Contributors

  • Daniel Overhoff - , Heidelberg University  (Author)
  • Peter Kohlmann - , Fraunhofer Institute for Digital Medicine (Author)
  • Alex Frydrychowicz - , Universitätsklinikum Schleswig-Holstein - Campus Lübeck (Author)
  • S. Gatidis - , University Hospital Tübingen (Author)
  • Christian Loewe - , Medical University of Vienna (Author)
  • Jan Moltz - , Fraunhofer Institute for Digital Medicine (Author)
  • Jan Martin Kuhnigk - , Fraunhofer Institute for Digital Medicine (Author)
  • Matthias Gutberlet - , Fresenius AG (Author)
  • H. Winter - , Hannover Medical School (MHH) (Author)
  • Martin Völker - , German Roentgen Society Deutsche Röntgengesellschaft (Author)
  • Horst Hahn - , Fraunhofer Institute for Digital Medicine (Author)
  • S. O. Schoenberg - , Heidelberg University  (Author)
  • U. Attenberger - (Author)
  • F. Bamberg - (Author)
  • B. Baeβler - (Author)
  • J. Barkhausen - (Author)
  • M. Forsting - (Author)
  • J. Furtner-Srajer - (Author)
  • S. Gatidis - (Author)
  • H. K. Hahn - (Author)
  • C. Herold - (Author)
  • A. Kaindl - (Author)
  • J. Kather - , Else Kröner Fresenius Center for Digital Health (Author)
  • R. Kikinis - (Author)
  • P. Kohlmann - (Author)
  • B. J. Krause - (Author)
  • G. Krombach - (Author)
  • M. E. Ladd - (Author)
  • G. Langs - (Author)
  • S. Lohwasser - (Author)
  • J. Lotz - (Author)
  • D. Pinto Dos Santos - (Author)
  • H. Prosch - (Author)
  • S. O. Schoenberg - (Author)
  • M. Völker - (Author)
  • H. Winther - (Author)
  • M. Zimmermann - (Author)
  • G. Antoch - (Author)
  • F. Anton - (Author)
  • J. Barkhausen - (Author)
  • A. Dörfler - (Author)
  • F. Körber - (Author)
  • G. Layer - (Author)
  • S. Neumann - (Author)
  • S. O. Schoenberg - (Author)
  • J. Weβling - (Author)
  • M. Wucherer - (Author)
  • R. Forstner - (Author)
  • E. R. Gizewski - (Author)
  • C. Herold - (Author)

Abstract

Purpose The DRG-ÖRG IRP (Deutsche Röntgengesellschaft-Österreichische Röntgengesellschaft international radiomics platform) represents a web-/cloud-based radiomics platform based on a public-private partnership.It offers the possibility of data sharing, annotation, validation and certification in the field of artificial intelligence, radiomics analysis, and integrated diagnostics. In a first proof-of-concept study, automated myocardial segmentation and automated myocardial late gadolinum enhancement (LGE) detection using radiomic image features will be evaluated for myocarditis data sets. Materials and Methods The DRG-ÖRP IRP can be used to create quality-assured, structured image data in combination with clinical data and subsequent integrated data analysis and is characterized by the following performance criteria: Possibility of using multicentric networked data, automatically calculated quality parameters, processing of annotation tasks, contour recognition using conventional and artificial intelligence methods and the possibility of targeted integration of algorithms. In a first study, a neural network pre-trained using cardiac CINE data sets was evaluated for segmentation of PSIR data sets. In a second step, radiomic features were applied for segmental detection of LGE of the same data sets, which were provided multicenter via the IRP. Results First results show the advantages (data transparency, reliability, broad involvement of all members, continuous evolution as well as validation and certification) of this platform-based approach. In the proof-of-concept study, the neural network demonstrated a Dice coefficient of 0.813 compared to the expert's segmentation of the myocardium. In the segment-based myocardial LGE detection, the AUC was 0.73 and 0.79 after exclusion of segments with uncertain annotation. The evaluation and provision of the data takes place at the IRP, taking into account the FAT (fairness, accountability, transparency) and FAIR (findable, accessible, interoperable, reusable) criteria. Conclusion It could be shown that the DRG-ÖRP IRP can be used as a crystallization point for the generation of further individual and joint projects. The execution of quantitative analyses with artificial intelligence methods is greatly facilitated by the platform approach of the DRG-ÖRP IRP, since pre-trained neural networks can be integrated and scientific groups can be networked. In a first proof-of-concept study on automated segmentation of the myocardium and automated myocardial LGE detection, these advantages were successfully applied. Our study shows that with the DRG-ÖRP IRP, strategic goals can be implemented in an interdisciplinary way, that concrete proof-of-concept examples can be demonstrated, and that a large number of individual and joint projects can be realized in a participatory way involving all groups. Key Points: The DRG-ÖRG IRP is a web/cloud-based radiomics platform based on a public-private partnership. The DRG-ÖRG IRP can be used for the creation of quality-assured, structured image data in combination with clinical data and subsequent integrated data analysis. First results show the applicability of left ventricular myocardial segmentation using a neural network and segment-based LGE detection using radiomic image features. The DRG-ÖRG IRP offers the possibility of integrating pre-trained neural networks and networking of scientific groups. Citation Format Overhoff D, Kohlmann P, Frydrychowicz A etal. The International Radiomics Platform - An Initiative of the German and Austrian Radiological Societies. Fortschr Röntgenstr 2021; 193: 276-287.

Details

Original languageEnglish
Pages (from-to)276-287
Number of pages12
JournalRoFo Fortschritte auf dem Gebiet der Rontgenstrahlen und der Bildgebenden Verfahren
Volume193
Issue number3
Publication statusPublished - 1 Mar 2021
Peer-reviewedYes

External IDs

PubMed 33242898

Keywords

Keywords

  • artificial intelligence, magnetic resonance imaging, myocarditis, neural networks